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| | 2-Methyl-5-nitroaniline Basic information |
| | 2-Methyl-5-nitroaniline Chemical Properties |
| Melting point | 103-106 °C(lit.) | | Boiling point | 294.61°C (rough estimate) | | density | 1.2333 (estimate) | | refractive index | 1.6276 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Crystalline Powder | | pka | 2.34±0.10(Predicted) | | color | Ochre to yellow-orange | | Water Solubility | <0.1 g/100 mL at 19 ºC | | BRN | 879021 | | Exposure limits | ACGIH: TWA 1 mg/m3 | | Stability: | Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, acids, chloroformates. | | CAS DataBase Reference | 99-55-8(CAS DataBase Reference) | | NIST Chemistry Reference | Benzenamine, 2-methyl-5-nitro-(99-55-8) | | IARC | 3 (Vol. 48) 1990 | | EPA Substance Registry System | 2-Methyl-5-nitroaniline (99-55-8) |
| | 2-Methyl-5-nitroaniline Usage And Synthesis |
| Chemical Properties | yellow powder | | Chemical Properties | 5-Nitro-o-toluidine is a yellow, crystalline
solid. | | Uses | 5-Nitro-o-toluidine is used in the synthesis of numerous dyes. | | Uses | 2-Methyl-5-nitroaniline may be employed as analytical standard for the surfactant mediated transformations (?254nm) of 2,4-dinitrotoluene. | | Preparation | 2-Methyl-5-nitrobenzenamine?in concentrated sulfuric acid nitration. | | Definition | ChEBI: A C-nitro compound in which the nitro compound is meta to the amino group and para to the methyl group of o-toluidine. | | General Description | Bright yellow powder. | | Air & Water Reactions | Insoluble in water. 2-Methyl-5-nitroaniline is sensitive to moisture, light, or prolonged exposure to air. | | Reactivity Profile | 2-Methyl-5-nitroaniline is incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides and chloroformates. | | Fire Hazard | Flash point data for 2-Methyl-5-nitroaniline are not available; however, 2-Methyl-5-nitroaniline is probably combustible. | | Safety Profile | Confirmed carcinogen
with experimental carcinogenic data.
Moderately toxic by ingestion. Mutation data
reported. Decomposes exothermically when
heated to 150℃. When heated to
decomposition it emits toxic fumes of NOx.
See also NITRO COMPOUNDS OF
AROMATIC HYDROCARBONS. | | Carcinogenicity | There
are no data available for evaluating carcinogenic risk to
humans. When 5-nitro-o-toluidine was administered in a
dietary feeding study to F344 rats (50 or 100 ppm) and
B6C3F1 mice (1200 or 2300 ppm) of both sexes, hepatocellular
carcinomas were produced in mice but not in rats. | | Shipping | UN2660 Nitrotoluidines (mono), Hazard Class:
6.1; Labels: 6.1-Poisonous materials. | | Purification Methods | Acetylate the aniline, and the acetyl derivative is crystallised to constant melting point; then hydrolyse it with 70% H2SO4 and the free base is regenerated by treatment with NH3 [Bevan et al. J Chem Soc 4284 1956]. [Beilstein 12 H 844. 12 IV 1807.] | | Incompatibilities | Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explosions.
Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides, acid chlorides; acid anhydrides;
chloroformates. | | Waste Disposal | Consult with environmental
regulatory agencies for guidance on acceptable disposal
practices. Generators of waste containing this contaminant
(≥100 kg/mo) must conform with EPA regulations governing
storage, transportation, treatment, and waste disposal. |
| | 2-Methyl-5-nitroaniline Preparation Products And Raw materials |
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