ChemicalBook Product Catalog Chemical Reagents Organic reagents fatty acid 3-Hydroxy-1-AdaMantane Carboxylic Acid

3-Hydroxy-1-AdaMantane Carboxylic Acid

3-Hydroxy-1-AdaMantane Carboxylic Acid Basic information
Product Name:3-Hydroxy-1-AdaMantane Carboxylic Acid
Synonyms:3-HYDROXYADAMANTANCARBOXYLIC ACID;3-HYDROXYADAMANTANE-1-CARBOXYLIC ACID;3-HYDROXYADAMANTANECARBOXYLIC ACID;AKOS BC-0508;1-HYDROXYADAMANTANE-3-CARBOXYLIC ACID;TIMTEC-BB SBB010113;3-Hydroxy-1-Adamantanecarboxylic Acid;3-Carboxyadamantan-1-ol
CAS:42711-75-1
MF:C11H16O3
MW:196.24
EINECS:
Product Categories:Adamantane derivatives;Carboxylic Acids;Carboxylic Acids;Ring Systems
Mol File:42711-75-1.mol
3-Hydroxy-1-AdaMantane Carboxylic Acid Structure
3-Hydroxy-1-AdaMantane Carboxylic Acid Chemical Properties
Melting point 203 °C
Boiling point 357.2±25.0 °C(Predicted)
density 1.419±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka4.60±0.40(Predicted)
form Solid
color Off-White
CAS DataBase Reference42711-75-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-22
Safety Statements 26-36/37/39-37/39-24/25
WGK Germany 3
HazardClass IRRITANT
HS Code 29181990
MSDS Information
ProviderLanguage
ALFA English
3-Hydroxy-1-AdaMantane Carboxylic Acid Usage And Synthesis
Chemical PropertiesWhite to yellow solid
Uses3-Hydroxy-1-AdaMantane Carboxylic Acid is used in the synthesis of potent pyridyl amide/sulfonamide inhibitors of 11β-HSD-1 which could be applied to a treatment of ulcers or in hormone therapy treatments relating t o cortisol.
Uses1-Carboxy-3-adamantanol is used in the synthesis of potent pyridyl amide/sulfonamide inhibitors of 11β-HSD-1 which could be applied to a treatment of ulcers or in hormone therapy treatments relating to cortisol.
Synthesis Reference(s)Synthetic Communications, 18, p. 1967, 1988 DOI: 10.1080/00397918808068263
3-Hydroxy-1-AdaMantane Carboxylic Acid Preparation Products And Raw materials
Preparation ProductsADAMANTANE-1-CARBOXYLIC ACID METHYL ESTER-->3-Fluoro-1-aminoadamantane hydrochloride-->3-Bromoadamantane-1-carboxylic acid
Saxagliptin Impurity 15 (S) - N- Boc- adamantylglycine 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2R)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1R,3S,5R)- Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3,5-dihydroxy-, (αS)- AKOS BB-9063 3-Hydroxyadamantane-1-acetic acid 1-Adamantanol Adamantane trans-4-Aminoadamantan-1-ol hydrochloride 1-Adamantanecarboxylic acid 1,4-Adamantandiol 4α-Hydroxyadamantane-1-carboxylic acid 1,3-Adamantanediol AKOS BBS-00006253 AKOS BB-9107 2β-Hydroxyadamantane-1-carboxylic acid 3-Hydroxy-1-AdaMantane Carboxylic Acid 1-HYDROXYADAMANTANE-3-CARBOXYLIC ACID ETHYL ESTER
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