ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Threonine derivatives H-THR(TBU)-OH

H-THR(TBU)-OH

H-THR(TBU)-OH Basic information
Product Name:H-THR(TBU)-OH
Synonyms:H-THR(BUT)-OH;H-THR(TBU)-OH;O-TERT-BUTYL-L-THREONINE;O-T-BUTYL-L-THREONINE HYDROCHLORIDE;O-T-BUTYL-L-THREONINE;THREONINE(TBU)-OH;(2S,3R)-2-amino-3-tert-butoxybutanoic acid;O-(tert-butyl)-L-threonine(SALTDATA: FREE)
CAS:4378-13-6
MF:C8H17NO3
MW:175.23
EINECS:610-143-6
Product Categories:Amino Acids;Amino Acids and Derivatives;Amino Acid Derivatives;Peptide Synthesis;Threonine
Mol File:4378-13-6.mol
H-THR(TBU)-OH Structure
H-THR(TBU)-OH Chemical Properties
Melting point 244-247 °C
Boiling point 275℃
density 1.055
Fp 120℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka2.14±0.10(Predicted)
form Solid
color White to Almost white
optical activity[α]20/D 43±2°, c = 1% in H2O
BRN 2206127
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29241990
MSDS Information
ProviderLanguage
SigmaAldrich English
H-THR(TBU)-OH Usage And Synthesis
Chemical PropertiesWhite powder
UsesO-tert-Butyl-L-threonine is a catalyst used in direct asymmetric Mannich, Mannich-type, and adol reaction involving unmodified α-hydroxyketones.
H-THR(TBU)-OH Preparation Products And Raw materials
Preparation ProductsFMOC-O-tert-Butyl-L-threonine
BPOC-THR(TBU)-OH CHA FMOC-THR(TBU)-OPFP Z-THR(TBU)-OH DCHA H-TYR-D-CYS(TBU)-GLY-PHE-LEU-THR(TBU)-OH Z-THR(TBU)-OME Fmoc-O-trityl-L-threonine O,O'-di-tert-butyl-L-threonine acetate Fmoc-O-tert·butyl-L-threonineN-carboxyanhydride H-THR(TBU)-OTBU H-THR(TBU)-OME HCL FMOC-L-THR(TBU)-OH,FMOC-THR(TBU)-OH,FMOC-O-TERT-BUTYL-L-THREONINE (FMOC-L-THR(TBU)-OH),Fmoc-O-tert-butyl-L-threonine, Fmoc-Thr(tBu)-OH Z-THR(TBU)-ONB BOC-L-THR(TBU)-OH,BOC-THR(TBU)-OH AC-THR(TBU)-OH Z-THR(TBU)-OTBU FMOC-THR(TBU)-ODHBT H-THR(TBU)-OTBU HCL H-THR(TBU)-OH
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