Clopidol

Clopidol Basic information
Product Name:Clopidol
Synonyms:3,5-dichloro-2,6-dimethyl-4-pyridino;ClopidolMeticlopidol;coccidiostatc;4-Pyridinol, 3,5-dichloro-2,6-dimethyl-;3,5-DICHLORO-2 98+%;Clopidol -Total dust;Clopidol, respirable dust;Clopindol
CAS:2971-90-6
MF:C7H7Cl2NO
MW:192.04
EINECS:221-008-2
Product Categories:Aromatics;Intermediates & Fine Chemicals;Food and Feed Additive;Active Pharmaceutical Ingredients;Veterinaries;Pharmaceuticals;Organics;2971-90-6
Mol File:2971-90-6.mol
Clopidol Structure
Clopidol Chemical Properties
Melting point >320℃
Boiling point 318.4±37.0 °C(Predicted)
density 1.2494 (rough estimate)
refractive index 1.5500 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility Aqueous Base (Slightly), Methanol (Slightly, Heated)
form neat
pka5.50±0.33(Predicted)
color White to Off-White
Water Solubility 40mg/L(temperature not stated)
Stability:Hygroscopic
InChIKeyQCMHHYSPKNVXLR-UHFFFAOYSA-N
CAS DataBase Reference2971-90-6(CAS DataBase Reference)
EPA Substance Registry SystemClopidol (2971-90-6)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 2
RTECS UU7711500
HS Code 29333990
Hazardous Substances Data2971-90-6(Hazardous Substances Data)
ToxicityLD50 orally in rats: 18 g/kg (Plisek)
MSDS Information
Clopidol Usage And Synthesis
DescriptionThe drug methylchlorpindol is used for the prevention of coccidiosis in poultry.
DescriptionClopidol is a coccidiostat. It prevents mortality of chickens infected with the parasites E. tenella, E. necatrix, E. acervuline, E. mivati, E. brunetti, and E. maxima. It has antimalarial activity against P. berghei in mice and P. cynomologi in rhesus macaques. Clopidol is a potential contaminant in food poultry. Formulations containing clopidol have been used in the prevention of coccidiosis in chickens.
Chemical PropertiesClopidol is a white to light brown powder.
Clopidol
UsesGABA Cl channel agonist, antiparasitic
UsesAn antibiotic used in veterinary medicine as a coccidiostat in poultry. Showed low order of acute and chronic toxicity in animals.
UsesAn antiprotozoal agent.
DefinitionA penta-substituted pyridine derivative.
General DescriptionWhite to light-brown, crystalline solid. Mp: 320°C. Practically insoluble in water. Administered to poultry to prevent the growth of pathogenic parasites.
Reactivity ProfileClopidol is a non-combustible as a solid, but dust may burn rapidly or explode when mixed with air and ignited.
HazardToxic. Mutagenic effects. Questionable carcinogen. Clopyralid.
Contact allergensThis drug is used for the prevention of coccidiosis in poultry.
Safety ProfileA nuisance dust. When heated to decomposition it emits very toxic fumes of Cland NOx.
Potential ExposureThose engaged in formulation, application or manufacture of this veterinary antibiotic. Used as a pharmaceutical and as feed and food additive
ShippingUN3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
IncompatibilitiesNoncombustible solid, but dust may explode in cloud form. Contact with strong oxidizers may cause a fire or explosion hazard
Waste DisposalDispose of contents and container to an approved waste disposal plant. All federal, state, and local environmental regulations must be observed. It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged, and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.
Clopidol Preparation Products And Raw materials
Raw materialsDehydroacetic acid-->4-Hydroxy-2,6-dimethylpyridine
4,4'-Bipyridine 2-Chloro-3-cyanopyridine N,N-Dimethylformamide Clopidogrel 2,6-Dimethylphenol Pentachloropyridine Dimethyl sulfide Dimethyl fumarate 2,6-Lutidine Clopidol Clopyralid Clioquinol Dimethyl sulfoxide 3,5-Dichloropyridine Fluroxypyr Dimethyl carbonate Dichloroethane Dimethyl phthalate

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