N-Boc-1-aminocyclobutanecarboxylic acid

N-Boc-1-aminocyclobutanecarboxylic acid Basic information

Product Name:	N-Boc-1-aminocyclobutanecarboxylic acid
Synonyms:	N-BOC-1-AMINOCYCLOBUTANE CARBOXYLIC ACID;1-AMINOCYCLOBUTYL-1-CARBOXYLIC ACID, N-BOC PROTECTED;1-(BOC-AMINO)CYCLOBUTANECARBOXYLIC ACID;1-N-BOC-AMINO-CYCLOBUTANE CARBOXYLIC ACID;1-(TERT-BUTYLOXYCARBONYL-AMINO)-CYCLOBUTYL-1-CARBOXYLIC ACID;1-Aminocyclobutane-1-carboxylic acid, N-BOC protected;Boc-1-amino-1-cyclobutane carboxylic acid, 97.5%;1-TERT-BUTOXYCARBONYLAMINO-CYCLOBUTANECARBOXYLIC ACID
CAS:	120728-10-1
MF:	C10H17NO4
MW:	215.25
EINECS:
Product Categories:	Peptide;pharmacetical;Amino Acids and Derivatives;White solid;LG
Mol File:	120728-10-1.mol

N-Boc-1-aminocyclobutanecarboxylic acid Chemical Properties

Melting point	129-133 °C(lit.)
Boiling point	362.1±21.0 °C(Predicted)
density	1.18±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Methanol
pka	4.14±0.20(Predicted)
form	Powder
color	White to light brown
BRN	7994003
InChIKey	ROVVUKFHORPDSM-UHFFFAOYSA-N
CAS DataBase Reference	120728-10-1(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

N-Boc-1-aminocyclobutanecarboxylic acid Usage And Synthesis

Uses	Boc-1-aminocyclobutane-1-carboxylic Acid is used in the synthesis of dipeptidyl nitriles with cathepsin-inhibiting activities. It is also used to prepare alkyl-oxo-aryl amides as novel antagonists of TRPA1 receptor.

N-Boc-1-aminocyclobutanecarboxylic acid Preparation Products And Raw materials

Raw materials	1-Aminocyclobutanecarboxylic acid-->5,7-Diaza-spiro[3.4]octane-6,8-dione -->Cyclobutanecarboxylic acid, 1-[[(1,1-diMethylethoxy)carbonyl]aMino]-, ethyl ester-->1-BROMO-CYCLOBUTANECARBOXYLIC ACID ETHYL ESTER
Preparation Products	(1-Cyano-cyclobutyl)-carbamic acid tert-butyl ester

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