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| | Dehydrocostus lactone Basic information |
| Product Name: | Dehydrocostus lactone | | Synonyms: | EPILIGULYL OXIDE;DEHYDROCOSTUSLACTONE;DEHYDROCOSTUS LACTONE hplc;(3aS,6aR,9aR,9bS)-Decahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2(3H)-one;DEHYDROCOSTUNOLIDE;Azuleno[4,5-b]furan-2(3H)-one,decahydro-3,6,9-;Costus lactone, dehydro-;tris(methylene)-,(3aS,6aR,9aR,9bS)- | | CAS: | 477-43-0 | | MF: | C15H18O2 | | MW: | 230.3 | | EINECS: | | | Product Categories: | Sesquiterpenoids;Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;Heterocycles;standardized herbal extract | | Mol File: | 477-43-0.mol |  |
| | Dehydrocostus lactone Chemical Properties |
| Melting point | 57.0 to 61.0 °C | | Boiling point | 140-143 °C(Press: 0.5 Torr) | | density | 1.09 | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | form | Solid | | color | White to Off-White | | Odor | nutty | | optical activity | [α]/D -14.0±3.0°, c = 1 in chloroform | | λmax | 206nm(MeOH)(lit.) | | InChIKey | NETSQGRTUNRXEO-XUXIUFHCSA-N | | LogP | 1.480 (est) | | CAS DataBase Reference | 477-43-0(CAS DataBase Reference) |
| Safety Statements | 24/25 | | HS Code | 29322090 |
| | Dehydrocostus lactone Usage And Synthesis |
| Description | A guaianolide sesquiterpene lactone extracted from
costus oil. Dehydrocostuslactone is one of the components
of lactone-mix, with costunolide and alantolactone,
used to detect Compositae-sensitive patients.
| | Description | Dehydrocostus lactone is a natural sesquiterpene first isolated from costus root, which is used in traditional medicine. Dehydrocostus lactone has diverse anti-cancer properties in cells and animal models, causing cell cycle arrest, inducing apoptosis, diminishing multidrug resistance, and suppressing angiogenesis in cancer cells. It also has anti-inflammatory actions in cells, including the inhibition of signaling through STAT1 and STAT3. | | Uses | Dehydrocostus lactone is the oil extracted from Saussurea lappa is used in perfumery and in the Orient for all kinds of diseases. | | Uses | Dehydrocostus Lactone is a compound known to be a growth regulator in plants. Known to affect cell viability and cell cycle distribution it may be useful in the application towards drug-resistant tumors. | | Definition | ChEBI: An organic heterotricyclic compound and guaianolide sesquiterpene lactone that is acrylic acid which is substituted at position 2 by a 4-hydroxy-3,8-bis(methylene)decahydoazulen-5-yl group and in which the hydroxy group and the carboxy group have undergone
formal condensation to afford the corresponding gamma-lactone. | | Contact allergens | A guaianolide sesquiterpene lactone extracted from costus oil. It is one of the components of Lactone mix, with costunolide and alantolactone, used to detect Compositae-sensitive patients. |
| | Dehydrocostus lactone Preparation Products And Raw materials |
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