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| | Piperaquine Basic information |
| Product Name: | Piperaquine | | Synonyms: | Piperaquine;Brn 0905079;Quinoline, 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis(7-chloro- (9ci);Quinoline, 4,4'-(trimethylenedi-4,1-piperazinediyl)bis(7-chloro-;Piperaquine USP/EP/BP | | CAS: | 83764-65-2 | | MF: | C29H32Cl2N6 | | MW: | 535.51058 | | EINECS: | | | Product Categories: | | | Mol File: | 83764-65-2.mol |  |
| | Piperaquine Chemical Properties |
| | Piperaquine Usage And Synthesis |
| Pharmaceutical Applications | A bisquinoline used to treat malaria in China since 1978. It
is structurally related to chloroquine, but active against chloroquine-
resistant P. falciparum. A combination with dihdyroartemisinin
has shown excellent tolerability and high cure
rates for multidrug-resistant falciparum malaria.
It is highly lipid-soluble and orally well absorbed. The elimination
half-life is 20–30 days and there is extensive metabolism.
Adverse effects are similar to chloroquine, but pruritus
is uncommon. |
| | Piperaquine Preparation Products And Raw materials |
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