METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE

METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE Basic information
Product Name:METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE
Synonyms:(2S)-3-Hydroxy-2-methylpropionic acid methyl ester;(S)-3-Hydroxy-2-methylpropanoic acid methyl ester;Methyl (S)-(+)-3-hydroxy-2-Methylpropionate, ee: 98%;L-(S)-(+)-3-HYDROXYISOBUTYRIC ACID METHYL ESTER;L(+)-BETA-HYDROXYISOBUTYRIC ACID METHYL ESTER;METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE;METHYL (S)-3-HYDROXY-2-METHYLPROPIONATE;METHYL (S)-(+)-3-HYDROXYISOBUTYRATE
CAS:80657-57-4
MF:C5H10O3
MW:118.13
EINECS:203-310-6
Product Categories:Building Blocks for Liquid Crystals;Chiral Building Blocks;Chiral Compounds (Building Blocks for Liquid Crystals);Esters (Chiral);Functional Materials;Synthetic Organic Chemistry
Mol File:80657-57-4.mol
METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE Structure
METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE Chemical Properties
Boiling point 74 °C/10 mmHg (lit.)
density 1.071 g/mL at 25 °C (lit.)
refractive index n20/D 1.425
Fp 178 °F
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Liquid
pka14.40±0.10(Predicted)
Specific Gravity1.07
color Colorless
optical activity[α]19/D +26°, c = 4 in methanol
Water Solubility Insoluble in water. Soluble in methanol.
BRN 1720830
CAS DataBase Reference80657-57-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 36/37/38-20/21/22
Safety Statements 26-36/37/39-36-24/25
RIDADR 1993
WGK Germany 3
HazardClass 3.2
PackingGroup III
HS Code 29181990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE Usage And Synthesis
Chemical PropertiesClear colorless liquid
UsesMethyl (S)-(+)-3-hydroxy-2-methylpropionate is used as a starting material for the synthesis of dictyostatin, discodermolide and spongidepsin.
METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE Preparation Products And Raw materials
Dimethyl diethylmalonate RESCINNAMINE Diethyl phenylmalonate Diethyl bis(hydroxymethyl)malonate Diethyl 2-bromo-2-methylmalonate diethyl (3,4,5-trimethoxybenzoyl)malonate 2,2,5-Trimethyl-1,3-dioxane-4,6-dione DIETHYL 2-(2-CYANOETHYL)MALONATE DIETHYL DIALLYLMALONATE DIETHYL DIETHYLMALONATE Triethyl methanetricarboxylate DIETHYL 2-ETHYL-2-(P-TOLYL)MALONATE DIETHYL DIMETHYLMALONATE 2,2-DIMETHYL-5-PHENYL-1,3-DIOXANE-4,6-DIONE 5-BROMO-2.2.5-TRIMETHYL-1.3-DIOXANE-4.6-DIONE TETRAETHYL 1,1,2,2-ETHANETETRACARBOXYLATE Diethyl 1,1-cyclopropanedicarboxylate (R)-(-)-3-HYDROXY-2-METHYLPROPIONIC ACID METHYL ESTER

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