ChemicalBook Product Catalog Biochemical Engineering Biochemical Reagents Biological Dyes 5-(TRIFLUOROMETHOXY)ISATIN

5-(TRIFLUOROMETHOXY)ISATIN

5-(TRIFLUOROMETHOXY)ISATIN Basic information
Product Name:5-(TRIFLUOROMETHOXY)ISATIN
Synonyms:5-(Trifluoromethoxy)isatin 97%;5-(trifluoroMethoxy)-2,3-dihydro-1H-indole-2,3-dione;5-(Trifluoromethoxy)indole-2,3-dione;5-(Trifluoromethoxy)-1H-indole-2,3-dione, 5-(Trifluoromethoxy)indoline-2,3-dione, 2,3-Dihydro-2,3-dioxo-5-(trifluoromethoxy)-1H-indole;5-(TRIFLUOROMETHOXY)ISATIN;5-(TRIFLUOROMETHOXYL)INDOLINE-2,3-DIONE;BUTTPARK 34\07-90;5-(Trifluoromethoxy)indoline-2,3-dione
CAS:169037-23-4
MF:C9H4F3NO3
MW:231.13
EINECS:1592732-453-0
Product Categories:Fused Ring Systems;Building Blocks;blocks;IndolesOxindoles;Heterocyclic Building Blocks;Indoles;Indane/Indanone and Derivatives
Mol File:169037-23-4.mol
5-(TRIFLUOROMETHOXY)ISATIN Structure
5-(TRIFLUOROMETHOXY)ISATIN Chemical Properties
Melting point 170-172 °C(lit.)
density 1.562±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka8.49±0.20(Predicted)
form powder to crystal
color Light yellow to Brown
Water Solubility Insoluble in water.
CAS DataBase Reference169037-23-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Safety Statements 24/25
WGK Germany 3
Hazard Note Irritant/Keep Cold
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
5-(TRIFLUOROMETHOXY)ISATIN Usage And Synthesis
Uses5-(Trifluoromethoxy)isatin is used as a reactant for preparation of oxindole derivatives as TAk1 kinase inhibitors and of isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors. It is also used as a reactant for synthesis of 3-substituted 2-indolinone RET kinase inhibitors and for preparation of indolone acetamides as antiseizure agents.
5-(TRIFLUOROMETHOXY)ISATIN Preparation Products And Raw materials
Preparation Products5-(TRIFLUOROMETHOXY)INDOLIN-2-ONE-->Methyl 5-(trifluoromethoxy)-1H-indazole-3-carboxylate
Trifluoromethoxybenzaldehyde2 2-(3-METHOXYPHENYL)ACETAMIDE 5-Methoxyoxindole 3'-(TRIFLUOROMETHOXY)ACETOPHENONE 3'-(Difluoromethoxy)acetophenone BUTTPARK 50\07-89 3-TRIFLUOROMETHOXYTOLUENE 3-(Difluoromethoxy)benzaldehyde 2,3-DIHYDROINDOL-5-OL 5-(TRIFLUOROMETHOXY)ISATIN 5-(TRIFLUOROMETHOXY)INDOLIN-2-ONE {2-[3-(Trifluoromethoxy)phenyl]ethyl}amine 5-HYDROXY ISATIN 5-Methoxy-2,3-dihydroindoline 7-TRIFLUOROMETHOXY-ISATIN 5-Methoxyisatin 2-METHYL-4-(TRIFLUOROMETHOXY)ANILINE 5-HYDROXYOXINDOLE
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