ChemicalBook Product Catalog API Nervous system drugs Antipsychotics CLOTHIAPINE

CLOTHIAPINE

CLOTHIAPINE Basic information
Product Name:CLOTHIAPINE
Synonyms:Etumine;f)(1,4)thiazepine,2-chloro-11-(4-methyl-1-piperazinyl)-dibenzo(;HF 2159;hf2159;LW 2159;lw2159;S-805C;CLOTHIAPINE
CAS:2058-52-8
MF:C18H18ClN3S
MW:343.87
EINECS:218-162-8
Product Categories:
Mol File:2058-52-8.mol
CLOTHIAPINE Structure
CLOTHIAPINE Chemical Properties
Melting point 121-123℃
Boiling point 163.4°C (rough estimate)
density 1.2405 (rough estimate)
refractive index 1.6000 (estimate)
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Off-white solid (m.p. 118-120°C).
pka7.22±0.42(Predicted)
Stability:Hygroscopic
Safety Information
ToxicityLD50 oral in rat: 280mg/kg
MSDS Information
CLOTHIAPINE Usage And Synthesis
UsesAntipsychotic.
DefinitionChEBI: Clotiapine is a dibenzothiazepine.
Safety ProfilePoison by ingestion. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl-, NOx, and SOx.
CLOTHIAPINE Preparation Products And Raw materials
Fluphenazine decanoate U-99194 MALEATE 2-phenyl-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol Bromocriptine mesylate LE 300 Piperazine palmitate R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride (+)-AJ 76 HYDROCHLORIDE BTCP HCL clopenthixol REMOXIPRIDE HYDROCHLORIDE Clozapine Clobetasol (RS)-TRANS-7-HYDROXY-2-[N-PROPYL-N-(3'-IODO-2'-PROPENYL)AMINO]TETRALIN MALEATE 11-(1-PIPERAZINYL)-DIBENZO[B,F][1,4]THIAZEPIN HYDROCHLORIDE 1-(3-CHLOROBENZYL)PIPERAZINE CLOTHIAPINE 11-(PIPERAZIN-1-YL)DIBENZO[B,F][1,4]THIAZEPINE Clotiapine
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