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| | DI-N-OCTYL PHTHALATE Basic information |
| | DI-N-OCTYL PHTHALATE Chemical Properties |
| Melting point | -25℃ | | Boiling point | 380 °C | | density | 0.980 g/mL at 20 °C(lit.) | | vapor pressure | 5(x 10-8 mmHg) at 82 °C, 500 at 132 °C (Gross and Colony, 1973) | | refractive index | n20/D 1.485 | | Fp | 219 °C | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Oily Liquid | | color | Colourless | | Specific Gravity | 0.98 | | Water Solubility | Insoluble in water. | | Merck | 14,2864 | | BRN | 1915994 | | Henry's Law Constant | 1.41(x 10-12 atm?m3/mol) at 25 °C (approximate - calculated from water solubility and vapor pressure) | | CAS DataBase Reference | 117-84-0(CAS DataBase Reference) | | NIST Chemistry Reference | Di-n-octyl phthalate(117-84-0) | | EPA Substance Registry System | Di-n-octyl phthalate (117-84-0) |
| Risk Statements | 60-61 | | Safety Statements | 23-24/25 | | RIDADR | 2810 | | WGK Germany | 2 | | RTECS | TI1925000 | | TSCA | Yes | | HS Code | 29173200 | | Hazardous Substances Data | 117-84-0(Hazardous Substances Data) | | Toxicity | Acute oral LD50 for mice 6,513 mg/kg (quoted, RTECS, 1985):rats 13,000 mg/kg (Dogra et al.,
1989):mice 1,250-1,954 mg/kg (Etnier, 1987). |
| | DI-N-OCTYL PHTHALATE Usage And Synthesis |
| Chemical Properties | Colorless liquid | | Physical properties | Clear, light colored, viscous, oily liquid with a slight odor | | Uses | Dioctyl phthalate is used as a plasticizer in various plastic materials. | | Uses | Phthalate ester used as plasticizers and additives. Used in toxicology studies as well as risk assessment studies of food contamination that occurs via migration of phthalates into foodstuffs from food-contact materials (FCM). | | Uses | Di-n-octyl phthalate is used as a plasticizer for many resins and elastomers. It acts as an additive. It is also used for medical tubing and blood storage bags, wire and cables, carpet back coating, floor tile and in cosmetics. | | Definition | ChEBI: Di-n-octyl phthalate is a phthalate ester and a diester. | | General Description | A clear liquid with a mild odor. Slightly less dense than water and insoluble in water. Hence floats on water. Flash point 430°F. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. As a liquid, can easily penetrate the soil and contaminate groundwater and nearby streams. Eye contact may produce severe irritation and direct skin contact may produce mild irritation. Used in the manufacture of a variety of plastics and coating products. | | Air & Water Reactions | Insoluble in water. | | Reactivity Profile | DI-N-OCTYL PHTHALATE reacts with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction with caustic solutions. Flammable hydrogen may be generated by mixing with alkali metals and hydrides. Can generate electrostatic charges by swirling or pouring [Handling Chemicals Safely, 1980. p. 250]. | | Health Hazard | Produces no ill effects at normal temperatures but may give off irritating vapor at high temperature. | | Health Hazard | The acute oral toxicity is very low. Inges tion may result in nausea, somnolence, hallucination, and lacrimation. In humans, sucheffects may be noted at a dose level of150–200 mg/kg. The recovery is prompt.The oral LD50 value in mice is in the range6500 mg/kg. Its irritant action on the skinand the eyes of rabbits was mild. Di-n-octylphthalate fed to mice at the 5% level in dietshowed no reproductive toxicity. | | Fire Hazard | Special Hazards of Combustion Products: None | | Safety Profile | Mildly toxic by
ingestion. Experimental teratogenic and
reproductive effects. A skin and severe eye
irritant. Used as a plasticizer. When heated
to decomposition it emits acrid smoke and
irritating fumes. See also ESTERS. | | Source | Detected in distilled water-soluble fractions of new and used motor oil at concentrations
of 1.3 to 1.4 and 73 to 78 μg/L, respectively (Chen et al., 1994). May leach from plastic products
(e.g., tubing, containers) used in laboratories during chemical analysis of aqueous samples. | | Environmental fate | Biological. o-Phthalic acid was tentatively identified as the major degradation product of di-noctyl
phthalate produced by the bacterium Serratia marcescens (Mathur and Rouatt, 1975). When
di-n-octyl phthalate was statically incubated in the dark at 25 °C with yeast extract and settled
domestic wastewater inoculum, no degradation was observed after 7 d. In a 21-d period, however,
gradual adaptation did occur, resulting in 94 and 93% losses at concentrations of 5 and 10 mg/L,
respectively (Tabak et al., 1981). In the presence of suspended natural populations from
unpolluted aquatic systems, the second-order microbial transformation rate constant determined in
the laboratory was reported to be 3.7 ± 0.6 x 10-13 L/organism?h (Steen, 1991).
Chemical/Physical. Under alkaline conditions, di-n-octyl phthalate will initially hydrolyze to noctyl
hydrogen phthalate and 1-octanol. The monoester will undergo hydrolysis forming ophthalic
acid and 1-octanol (Kollig, 1993). The hydrolysis half-life at pH 7 and 25 °C was
estimated to be 107 yr (Ellington et al., 1988). |
| | DI-N-OCTYL PHTHALATE Preparation Products And Raw materials |
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