2-Fluoro-3-pyridylboronic acid

2-Fluoro-3-pyridylboronic acid Basic information

Product Name:	2-Fluoro-3-pyridylboronic acid
Synonyms:	2-Fluoropyridine-3-boronic acid,97%;3-Borono-2-fluoropyridine;2-Fluoropyridine-3-boronic Acid ;2-Fluoropyridine-3-boronic Acid (contains varying aMounts of Anhydride);2-fluoropyridin-3-yl-3-boronic acid;2-Fluoro-3-pyridylboronic;(2-Fluoropyridin-3-yl)boronic acid hydrate;2-Fluoro-3-pyridylboronic acid 2-Fluoropyridine-3-boronic acid
CAS:	174669-73-9
MF:	C5H5BFNO2
MW:	140.91
EINECS:
Product Categories:	Boronate Ester;Potassium Trifluoroborate;PYRIDINE;HALIDE;blocks;Boronic Acids & Esters;BoronicAcids;Pyridines;Fluorinated;Organoborons;Boronic acid;Boronic Acids & Esters;Boric acid series
Mol File:	174669-73-9.mol

2-Fluoro-3-pyridylboronic acid Chemical Properties

Melting point	274-283 °C
Boiling point	322.6±52.0 °C(Predicted)
density	1.34±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	soluble in Methanol
pka	6.68±0.58(Predicted)
form	solid
color	white
BRN	9119935
CAS DataBase Reference	174669-73-9(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
ALFA	English

2-Fluoro-3-pyridylboronic acid Usage And Synthesis

Chemical Properties	White powder
Uses	Reactant involved in: Heterocyclization eith α-oxocarboxylic acids Suzuki-Miyaura coupling reactions Additionally used as a precursor to biologically active molecules including: Heteroaryl benzylureas with glycogen synthase kinase 3 inhibitory activity Carboxyindoles with HCV NS5B polymerase inhibitory activity Pyrazolyl- and thienyl-aminohydantoins with BACE1 inhibitory activity

2-Fluoro-3-pyridylboronic acid Preparation Products And Raw materials

Raw materials	Diethyl ether-->Nitrogen-->Triisopropyl borate-->Lithium diisopropylamide-->2-Fluoropyridine
Preparation Products	5-CHLORO-2'-FLUORO-[2,3']-BIPYRIDINE

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