ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Amino alcohol derivative N-Methyl-L-prolinol

N-Methyl-L-prolinol

N-Methyl-L-prolinol Basic information
Uses
Product Name:N-Methyl-L-prolinol
Synonyms:(2S)-1-Methyl-2-pyrrolidinemethanol;(2S)-1-Methyl-2α-(hydroxymethyl)pyrrolidine;(2S)-1-Methyl-2α-pyrrolidinemethanol;(2S)-1-Methylpyrrolidine-2α-methanol;(S)-(+)-1-methyl-prolinol;(S)-(-)-2-HYDROXYMETHYL-1-METHYLPYRROLID;(S)-(1-Methylpyrrolidin-2-yl)Methanol;(S)-(-)-1-Methyl-2-pyrrolidinemethanol 96%
CAS:34381-71-0
MF:C6H13NO
MW:115.17
EINECS:251-981-9
Product Categories:chiral;Chiral Reagent
Mol File:34381-71-0.mol
N-Methyl-L-prolinol Structure
N-Methyl-L-prolinol Chemical Properties
alpha -49.5 º (c=5, MeOH)
Boiling point 67-69 °C12 mm Hg(lit.)
density 0.968 g/mL at 25 °C(lit.)
refractive index n20/D 1.469(lit.)
Fp 146 °F
storage temp. 2-8°C
pka14.77±0.10(Predicted)
form Liquid
color Colorless to yellow
optical activity[α]19/D 49.5°, c = 5 in methanol
BRN 79851
CAS DataBase Reference34381-71-0(CAS DataBase Reference)
NIST Chemistry ReferenceN-Methyl-L-prolinol(34381-71-0)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 23-24/25-36-26
WGK Germany 3
F 8-10-23
HazardClass IRRITANT
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
N-Methyl-L-prolinol Usage And Synthesis
UsesN-Methyl-L-prolinol is a reagent used in the synthesis of novel 4-hydroxytamoxifen analogs used as estrogen-related receptor γ (ERRγ) inverse agonists.
Chemical Propertieswhite to light yellow crystal powde
UsesPrecursor to phosphine ligands for catalytic asymmetric Grignard cross-coupling reactions.
N-Methyl-L-prolinol Preparation Products And Raw materials
Preparation Products(2S)-2-(broMoMethyl)-1-Methyl-Pyrrolidine
Z-PRO-ONP SWAINSONINE 1-Methylpyrrolidine Methyl N-Methyl-L-proline Z-L-PROLINE (S)-(-)-2-(METHOXYMETHYL)-1-PYRROLIDINECARBOXALDEHYDE Polyvinylpyrrolidone (S)-(-)-1-BENZYL-2-PYRROLIDINEMETHANOL 4-METHOXY-2-METHYLBENZOIC ACID GLYCYL-L-PROLINE PHE-PRO N-Methyl-L-prolinol Thiophanate-methyl L-(+)-Prolinol Methyl acrylate Methyl acetate Methyl bromide
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