(+/-)-8-PRENYLNARINGENIN

(+/-)-8-PRENYLNARINGENIN Basic information

Product Name:	(+/-)-8-PRENYLNARINGENIN
Synonyms:	(±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-Methyl-2-butenyl)-4H-1-benzopyran-4-one;2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-Methyl-2-buten-1-yl)-4H-1-benzopyran-4-one;rac 8-Prenylnaringenin;4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-;Naringenin 8-Prenyl Racemate;(+/-)-8-PRENYLNARINGENIN
CAS:	68682-02-0
MF:	C20H20O5
MW:	340.37
EINECS:	245-096-7
Product Categories:	Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:	68682-02-0.mol

(+/-)-8-PRENYLNARINGENIN Chemical Properties

Melting point	183-184 °C
Boiling point	597.6±50.0 °C(Predicted)
density	1.314±0.06 g/cm3(Predicted)
storage temp.	−20°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Light yellow powder
pka	7.70±0.40(Predicted)
color	Off-White to Pale Yellow
Stability:	Light Sensitive

Safety Information

Safety Statements	22-24/25
WGK Germany	3

MSDS Information

(+/-)-8-PRENYLNARINGENIN Usage And Synthesis

Description	(±)-8-Prenylnaringenin ((±)-8-PN) is a prenylflavonoid with potent estrogenic activity that can be isolated from hops. It inhibits both isoforms of the human estrogen receptor (ER; IC₅₀s = 57 and 68 nM for ERα and ERβ, respectively). (±)-8-PN is effective in vivo, suppressing loss of bone mineral density in ovariectomized rats and blocking changes in tail skin temperature in a rat model of postmenopausal hot flashes.
Uses	8-Prenylnaringenin is a prenylflavonoid, a class on non-steroidal phytoestrogen that mimicks and/or modulating endogenous estrogens via estrogen receptor binding.
Definition	ChEBI: Rac 8-Prenylnaringenin is a member of flavanones.

(+/-)-8-PRENYLNARINGENIN Preparation Products And Raw materials

Preparation Products

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