|  | |  |  | 2,4,4'-TRIHYDROXYBENZOPHENONE Basic information | 
 | Product Name: | 2,4,4'-TRIHYDROXYBENZOPHENONE |  | Synonyms: | 2,4,4'-Trihydroxybenzophenone 95%;(2,4-dihydroxyphenyl)(4-hydroxyphenyl)-methanon;2,4-Dihydroxyphenyl p-hydroxybenzyl ketone;Methanone, (2,4-dihydroxyphenyl)(4-hydroxyphenyl)-;2,4,4'-TRIHYDROXYBENZOPHENONE;(2,4-DIHYDROXY-PHENYL)-(4-HYDROXY-PHENYL)-METHANONE;LABOTEST-BB LT00159581;2,4,4-TRIHYDROXYBENZOPHENONE 98+% |  | CAS: | 1470-79-7 |  | MF: | C13H10O4 |  | MW: | 230.22 |  | EINECS: | 216-004-2 |  | Product Categories: | Building Blocks;C13 to C14;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Benzophenones (for High-Performance Polymer Research);Functional Materials;Reagent for High-Performance Polymer Research;C13  to  C14;Carbonyl  Compounds;Ketones;Industrial/Fine Chemicals |  | Mol File: | 1470-79-7.mol |  |  | 
|  |  | 2,4,4'-TRIHYDROXYBENZOPHENONE Chemical Properties | 
 | Melting point | 197-198 °C(lit.) |  | Boiling point | 332.2°C (rough estimate) |  | density | 1.2683 (rough estimate) |  | refractive index | 1.4977 (estimate) |  | Water Solubility | Slightly soluble in water |  | form | powder to crystal |  | pka | 7.59±0.35(Predicted) |  | color | White to Light yellow to Light orange |  | CAS DataBase Reference | 1470-79-7(CAS DataBase Reference) | 
|  |  | 2,4,4'-TRIHYDROXYBENZOPHENONE Usage And Synthesis | 
 | Chemical Properties | orange powder or chunks |  | Uses | 2,4,4''-Trihydroxybenzophenone is a small molecule inhibitor of viral replication. |  | Preparation | Preparation by reaction of 4-hydroxybenzoic acid with resorcinol, ? in the presence of zinc chloride at 160° (Nencki reaction);
 ? in the presence of zinc chloride and phosphorous oxychloride for 4 days at r.t. (78%);
 in the presence of zinc chloride and a mixture of polyphosphoric acid/85% phosphoric acid (60:40) at 27°. Then, during 2 h, phosphorous trichloride was added between 27° and 37° and the mixture heated at 60° for 16 h (quantitative yield);
 ? in the presence of hydrofluoric acid at 75° in an autoclave.
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|  |  | 2,4,4'-TRIHYDROXYBENZOPHENONE Preparation Products And Raw materials | 
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