5-Azacytosine

5-Azacytosine Basic information
Product Name:5-Azacytosine
Synonyms:5-triazin-2(1h)-one,4-amino-3;2-Amino-4-hydroxy-1,3,5-triazine;2-AMINO-4-HYDROXY-S-TRIAZINE;4-AMINO-1,3,5-TRIAZIN-2-ONE;4-AMINO-1,3,5-TRIAZINE-2[1H]-ONE;4-AMINO-S-TRIAZIN-2(1H)-ONE;5-AZACYTOSINE;5-Azacytosine,98%
CAS:931-86-2
MF:C3H4N4O
MW:112.09
EINECS:213-242-9
Product Categories:Pyrimidine purine;Heterocyclic Compounds;Amino Acids;Bases & Related Reagents;Inhibitors;Nucleotides;All Inhibitors;Pyrimidines;bc0001;931-86-2
Mol File:931-86-2.mol
5-Azacytosine Structure
5-Azacytosine Chemical Properties
Melting point >300 °C (lit.)
Boiling point 209.98°C (rough estimate)
density 1.86
refractive index 1.8010 (estimate)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Aqueous Base (Slightly, Heated), DMSO (Slightly, Heated)
form Solid
pka7.61±0.10(Predicted)
color White to Off-White
BRN 116378
InChIKeyMFEFTTYGMZOIKO-UHFFFAOYSA-N
CAS DataBase Reference931-86-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 3
RTECS XZ2854300
HS Code 29336990
MSDS Information
ProviderLanguage
5-Azacytosine English
SigmaAldrich English
ACROS English
5-Azacytosine Usage And Synthesis
Chemical PropertiesCrystalline Solid
Uses5-Azacytosine can inhibits the growth of Escherichia coli and used as the most effective cytosine mimics for the design of novel antiviral and anti-tumor drug candidates.
UsesReactant for:
  • Enzymic synthesis of nucleoside analogs using immobilized 2′-deoxyribosyltransferase from Lactobacillus reuteri
  • Reactions with oxide radical ion

  • Potential antitumor and antiproliferative agent against human leukemia cells
DefinitionChEBI: A monoamino-1,3,5-triazine that is cytosine in which the aromatic CH at position 5 is replaced by a nitrogen.
5-Azacytosine Preparation Products And Raw materials
beta-Methyl vinyl phosphate (MAP) Betaine Cytosine 3-Aminoacetophenone ALTRENOGEST 5-Azacytidine / 5-Azacytosine Buprofezin 5-METHYLCYTOSINE Glycine 2-Aminoacetophenone Metribuzin Fluorocytosine ANILAZINE Toltrazuril AMINO ACIDS CHLOROPHOSPHONAZO III 1,3,5-Triazine 4-Aminoacetophenone

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