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| | Cefotiam hydrochloride Basic information |
| Product Name: | Cefotiam hydrochloride | | Synonyms: | cefotiam hydrochloride;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-, dihydrochloride, (6R,7R)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-, dihydrochloride, (6R-trans)-;Abbott 48999;Halospor;Pansporin;Pansporine;Spizef | | CAS: | 66309-69-1 | | MF: | C18H23N9O4S3.HCl | | MW: | 562.08 | | EINECS: | 266-312-6 | | Product Categories: | ANTRYPOL;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 66309-69-1.mol |  |
| | Cefotiam hydrochloride Chemical Properties |
| Melting point | >93°C (dec.) | | Boiling point | 94℃ | | RTECS | XI0367000 | | Fp | >110°(230°F) | | storage temp. | Inert atmosphere,2-8°C | | solubility | H2O: ≥22M | | form | powder | | color | white to tan | | Water Solubility | Soluble in water | | Stability: | Hygroscopic | | InChIKey | BWRRTAXZCKVRON-DGPOFWGLSA-N | | CAS DataBase Reference | 66309-69-1(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36 | | Safety Statements | 26 | | WGK Germany | 3 | | HS Code | 2941906000 |
| | Cefotiam hydrochloride Usage And Synthesis |
| Uses | Cefotiam hydrochloride (SCE-963 hydrochloride) is a parenteral cephalosporin antibiotic. Cefotiam has broad-spectrum activity against Gram-positive and Gram-negative bacteria. | | Definition | ChEBI: Cefotiam dihydrochloride is the dihydrochloride salt of cefotiam. It has a role as an antibacterial drug. It contains a cefotiam. | | Brand name | Ceradon (Takeda). | | Pharmacokinetics | Cefotiam Hydrochloride is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted. |
| | Cefotiam hydrochloride Preparation Products And Raw materials |
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