N-Succinimidyl S-Acetylthioglycolate

N-Succinimidyl S-Acetylthioglycolate Basic information
Product Name:N-Succinimidyl S-Acetylthioglycolate
Synonyms:n-hydroxysuccinimides-acetylthioacetate;SUCCINIMIDYL ACETYLTHIOACETATE;SATA;S-ACETYLTHIOGLYCOLIC ACID NHS ESTER;S-ACETYLTHIOGLYCOLIC ACID N-HYDROXYSUCCINIMIDE ESTER;S-ACETYLTHIOGLYCOLIC ACID N-SUCCINIMIDYL ESTER;S-ACETYLTHIOACETIC ACID-N-HYDROXYSUCCINIMIDE ESTER;N-SUCCINIMIDYL (ACETYLTHIO)ACETATE
CAS:76931-93-6
MF:C8H9NO5S
MW:231.23
EINECS:678-479-6
Product Categories:MTS & Sulfhydryl Active Reagents;Building Blocks;Chemical Biology;Chemical Synthesis;Crosslinkers;Crosslinking;Heterobifunctional Cross-Linking Reagents;Linkers and Crosslinkers;Organic Building Blocks;Protected Thiols/Mercaptans;Protein Modification;Protein Structural Analysis;Proteomics;Sulfur Compounds;MTS and Sulfhydryl Active Reagents;N-Substituted Maleimides, Succinimides & Phthalimides;N-Substituted Succinimides;Heterocycles;Protein Modification Reagents;proteinmod
Mol File:76931-93-6.mol
N-Succinimidyl S-Acetylthioglycolate Structure
N-Succinimidyl S-Acetylthioglycolate Chemical Properties
Melting point 84-89 °C
Boiling point 337.3±44.0 °C(Predicted)
density 1.46±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility acetonitrile: 50 mg/mL
form powder
color White to Off-White
BRN 7815491
Stability:Moisture Sensitive
Safety Information
Safety Statements 25/26
WGK Germany 3
3-10-23
HS Code 29309090
MSDS Information
ProviderLanguage
SigmaAldrich English
N-Succinimidyl S-Acetylthioglycolate Usage And Synthesis
Chemical PropertiesWhite to Off-White Solid
UsesN-Succinimidyl S-Acetylthioglycolate can be used as Thiolating reagent for primary amines; thiol can be deprotected under mild conditions and be useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
UsesThiolating reagent for primary amines; thiol can be deprotected under mild conditions. Typically, couples initially to a molecule containing primary amine by amide bond buffered at pH 7.5. Deprotection may be accomplished with 0.05 M hydroxylamine at neutral pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
UsesReacts with primary amines to add protected sulfhydryls.
N-Succinimidyl S-Acetylthioglycolate Preparation Products And Raw materials
N-(2-AMINOETHYL)MALEIMIDE TRIFLUOROACETA (S)-(-)-N-(1-PHENYLETHYL)MALEIMIDE 2-IMINOTHIOLANE N-Hydroxysulfosuccinimide sodium salt N-Hydroxysuccinimide ethyl ethanethioate satA protein N-METHOXY-N-METHYL-PROPIONAMIDE S-ACETYL-DPEG 4 ACID (DPEG 4 SATA ACID) S-ACETYL-DPEG 8 ACID (DPEG 8 SATA ACID) S-ACETYL-DPEG 8 NHS ESTER (DPEG 8 SATA) N-Acetoxysuccinimide N-Succinimidyl S-Acetylthioglycolate N-Methoxy-N-methylacetamide S-ACETYL-DPEG 4 NHS ESTER (DPEG 4 SATA) N,N,O-TRIACETYLHYDROXYLAMINE N-METHOXYDIACETAMIDE S-ACETYLTHIOACETIC ACID

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