D-Aspartic acid

D-Aspartic acid Basic information

Product Name:	D-Aspartic acid
Synonyms:	(R)-(-)-AMINOSUCCINIC ACID;(R)-AMINOSUCCINIC ACID;(R)-(-)-ASPARTIC ACID;1-Amino-1,2-carboxyethane;d-aspartic;d-asparticaci;l-Asparagic acid;H-D-Asp
CAS:	1783-96-6
MF:	C4H7NO4
MW:	133.1
EINECS:	217-234-6
Product Categories:	Amino Acids & Derivatives;Aromatics;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals;amino;Aspartic acid [Asp, D];Amino Acids and Derivatives;for Resolution of Bases;alpha-Amino Acids;Amino Acids;Biochemistry;Optical Resolution;Synthetic Organic Chemistry;Amino ACIDS SERIES;chiral;Amino Acid Derivatives;Amino Acids;Glutamate receptor;amino acid;aspartic acid;chemicals;organic acids;pharmaceutical intermediate;bc0001
Mol File:	1783-96-6.mol

D-Aspartic acid Chemical Properties

Melting point	>300 °C(lit.)
alpha	-25.8 º (c=5, 5N HCl)
Boiling point	245.59°C (rough estimate)
density	1.66
refractive index	-25 ° (C=8, 50% HCl)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Aqueous Acid (Sparingly)
form	Crystalline Powder
pka	pK1: 1.89(0);pK2: 3.65;pK3: 9.60 (25°C)
color	White to off-white
optical activity	[α]20/D 24°, c = 2.3 in 6 M HCl
Water Solubility	SOLUBLE
Merck	14,840
BRN	1723529
InChIKey	CKLJMWTZIZZHCS-UWTATZPHSA-N
LogP	-1.075 (est)
CAS DataBase Reference	1783-96-6(CAS DataBase Reference)
NIST Chemistry Reference	D-aspartic acid(1783-96-6)

Safety Information

Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38
Safety Statements	24/25-36-26
WGK Germany	3
RTECS	CI9097500
HS Code	29224995

MSDS Information

Provider	Language
D-Aminosuccinic acid	English
SigmaAldrich	English
ACROS	English
ALFA	English

D-Aspartic acid Usage And Synthesis

Chemical Properties	White or almost white crystalline powder
Uses	A non-essential amino acid found in food sources and dietary supplements. D-Aspartic acid's conjugate base D-aspartate has potential use as a a therapeutic agent in the treatment of schizophrenia-related symptoms.
Uses	D-Aspartic acid modulates melatonin synthesis in the pineal gland.
Definition	ChEBI: The D-enantiomer of aspartic acid.
Biological Activity	Endogenous NMDA receptor agonist with similar activity to the L-isomer (L-Aminosuccinic acid ). Also a non-metabolizable substrate for EAA uptake systems. Modulates melatonin synthesis in the pineal gland.
storage	Room temperature

D-Aspartic acid Preparation Products And Raw materials

Preparation Products

(R)-(+)-1-Boc-3-aminopyrrolidine-->(R)-3-(Boc-amino)pyrrolidine-->3-oxopropanoic acid-->N-ACETYL-D-ASPARTIC ACID-->D-Aspartic acid, 1,4-diethyl ester-->Fmoc-D-Aspartic acid-4-methyl ester

BOC-D-ASP(OBZL)-OH LABOTEST-BB LT00455678 Fmoc-D-Aspartic acid beta-tert-butyl ester MESO-2,3-DIAMINOSUCCINIC ACID DL-THREO-BETA-HYDROXYASPARTIC ACID BOC-D-ASP(OTBU)-OH DCHA Boc-D-aspartic acid 4-cyslohexyl ester D-ASPARTIC ACID DIMETHYL ESTER HYDROCHLORIDE GLYCYL-D-ASPARTIC ACID Ascoric Acid FMOC-D-ASP(OCHEX)-OH N-Benzyloxycarbonyl-D-aspartic acid D-ASPARTIC ACID(OBZL)-OBZL P-TOSYLATE Stearic acid H-D-ASP-OBZL D-Aspartic acid Boc-D-aspartic acid 4-benzyl ester FMOC-ASN(TRT)-OPFP

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