ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Alanine derivatives L-Cyclohexylalanine

L-Cyclohexylalanine

L-Cyclohexylalanine Basic information
Description References
Product Name:L-Cyclohexylalanine
Synonyms:(S)-CYCLOHEXYLALANINE;3-CYCLOHEXYL-L-ALANINE HYDROCHLORIDE;3-CYCLOHEXYL-L-ALANINE HYDROCHLORIDE SALT;3-CYCLOHEXYL-L-ALANINE;H-CHA-OH;H-CHA-OH HCL;H-BETA-CYCLOHEXYL-ALA-OH HCL;HEXAHYDRO-L-PHENYLALANINE HCL
CAS:27527-05-5
MF:C9H17NO2
MW:171.24
EINECS:1308068-626-2
Product Categories:chiral
Mol File:27527-05-5.mol
L-Cyclohexylalanine Structure
L-Cyclohexylalanine Chemical Properties
Melting point 322 °C
Boiling point 307.1±25.0 °C(Predicted)
density 1.075±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
pka2.33±0.10(Predicted)
form Solid
CAS DataBase Reference27527-05-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-37/39-26
WGK Germany 3
F 10
Hazard Note Irritant
HS Code 2922498590
MSDS Information
L-Cyclohexylalanine Usage And Synthesis
DescriptionL-Cyclohexylalanine is a kind of amino acid analog. It has some pharmacological effects. Study has shown that some of its derivatives exhibit potent bactericidal activity against drug-resistant gram-positive pathogens. Its derivatives can also act as dipeptidyl peptidase-IV inhibitor, which can be used for the treatment or prevention of diabetes. 
Referenceshttp://nizetlab.ucsd.edu/Publications/CombinatorialLibrary.pdf
Duffy, Joseph L, et al. "Cyclohexylalanine derivatives as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes." CN, CN 1960990 A. 2007.
Aarstad, K, T. L. Zimmer, and S. G. Laland. "The fidelity of gramicidin S synthetase." European Journal of Biochemistry 112.2(1980):335-338.

Chemical Propertieswhite to light yellow crystal powder
Uses(S)-(+)-Cyclohexylalanine
L-Cyclohexylalanine Preparation Products And Raw materials
Preparation ProductsZ-3-CYCLOHEXYL-L-ALANINE
Perindoprilat Cyclohexanecarboxylic acid BOC-CHA-OH DCHA 1H-Indole-2-carboxylicacid,octahydro-,(2S)-(9CI) L-CYCLOHEXYLALANINE METHYL ESTER HCL CBZ-L-CYCLOHEXYLALANINE Perindopril erbumine Glycine Indolapril Cyclohexanemethanol L-Cyclohexylalanine Cyclohexylbenzene H-D-ARG-ARG-PRO-HYP-GLY-THI-SER-D-TIC-OIC-OH N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-CYCLOHEXYLALANINE,FMOC-L-CYCLOHEXYLALANINE,FMOC-L-3-CYCLOHEXYLALANINE Isocyanatocyclohexane Trandolapril Molasses BOC-D-CYCLOHEXYLALANINE,BOC-D-CYCLOHEXYLALANINE 2H2O
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