Fenipentol

Fenipentol Basic information
Product Name:Fenipentol
Synonyms:1-PHENYLHYDROXYPENTANE;2-(4-Hydroxybenzoyloxy)-N,N,N-trimethylethanaminium;p-Hydroxybenzoylcholine;BenzeneMethanol, a-butyl-;D52;N8L;PrLZ;1-Hydroxy-1-phenylpentane
CAS:583-03-9
MF:C11H16O
MW:164.25
EINECS:209-493-9
Product Categories:583-03-9
Mol File:583-03-9.mol
Fenipentol Structure
Fenipentol Chemical Properties
Melting point <25 °C
Boiling point 137°C 2mm
density 0,96 g/cm3
refractive index 1.5080
Fp 137°C/2mm
storage temp. Sealed in dry,Room Temperature
form clear liquid
pka14.43±0.20(Predicted)
color Colorless to Almost colorless
Merck 14,3975
BRN 1908761
CAS DataBase Reference583-03-9(CAS DataBase Reference)
NIST Chemistry ReferenceFenipentol(583-03-9)
EPA Substance Registry SystemBenzenemethanol, .alpha.-butyl- (583-03-9)
Safety Information
Safety Statements 24/25
RTECS DN8780000
TSCA Yes
HS Code 2906.29.6000
MSDS Information
ProviderLanguage
ALFA English
Fenipentol Usage And Synthesis
OriginatorPancoral,Eisai,Japan,1973
UsesBiliary dyskinesia;Choleretic
DefinitionChEBI: Fenipentol is a member of benzenes.
Manufacturing ProcessThe 1-phenylpentanol-(1) may be prepared in any convenient manner. Benzaldehyde may be reacted with n-butyl-magnesium bromide, and after purification 1-phenyl-pentanol-(1) is obtained in the form of a colorless oil at room temperature.
Therapeutic FunctionCholeretic
Synthesis Reference(s)Tetrahedron Letters, 25, p. 5187, 1984 DOI: 10.1016/S0040-4039(01)81559-8
Safety ProfilePoison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Stimulates the production of bile by the liver. When heated to decomposition it emits acrid smoke and irritating fumes.
Fenipentol Preparation Products And Raw materials
Raw materialsMagnesium-->Benzaldehyde-->1-Bromobutane
Preparation Products2-BROMO-1-PHENYL-PENTAN-1-ONE
Pentanol LOBELANIDINE HCL 1-PENTANOL, 3-METHYL-5-PHENYL butylphenylcarbinol Vitexin Methyl cyclopentylphenylglycolate Rosin pentaerythrityl ester Polyol benzoate Dipentaerythritol VITEXIN-4'-RHAMNOSIDE(RG) TIMTEC-BB SBB006499 HOMOORIENTIN Hexocyclium (+)-Taddol Cyclohexyl(phenyl)methanol Fenipentol PHENYL VALERATE CYCLOBUTYL-HYDROXY-PHENYL-ACETIC ACID

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