Methyl L-tyrosinate

Methyl L-tyrosinate Basic information

Product Name:	Methyl L-tyrosinate
Synonyms:	(S)-2-Amino-3-(p-hydroxyphenyl)propionic acid methyl ester;(S)-3-(4-Hydroxyphenyl)-2-aminopropionic acid methyl ester;L-Tyrosine methyl;L-Tyrosine methyl ester,98%;L-Tyr-Ome;L-Tyrosine methyl es;L-Tyrosine Methyl ester, 98% 100GR;(S)-Methyl 2-aMino-3-(4-hydroxyphenyl)propanoate
CAS:	1080-06-4
MF:	C10H13NO3
MW:	195.22
EINECS:	214-095-3
Product Categories:	Amino Acids & Derivatives;Aromatics;Tyrosine [Tyr, Y];Amino Acid Derivatives;Peptide Synthesis;Tyrosine;Amino Acids and Derivatives;Amino Acids 13C, 2H, 15N
Mol File:	1080-06-4.mol

Methyl L-tyrosinate Chemical Properties

Melting point	134-136 °C (lit.)
alpha	25 º (c=2.4, CH3OH)
Boiling point	331.88°C (rough estimate)
density	1.1926 (rough estimate)
refractive index	1.5150 (estimate)
storage temp.	2-8°C
solubility	Chloroform, Ethyl Acetate, Methanol
pka	pKa 7.04±0.02(H2O t=25.0±0.1 I=0.1(NaCl) N2atmosphere) (Uncertain);9.73±0.03(H2O t=25.0±0.1 I=0.1(NaCl) N2atmosphere) (Uncertain)
form	Crystalline Powder or Crystals
color	White to yellow
optical activity	[α]20/D +26°, c = 2.4 in methanol
Water Solubility	Soluble in water.
BRN	2372626
Stability:	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	1080-06-4(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Safety Statements	22-24/25
WGK Germany	3
HazardClass	IRRITANT
HS Code	29225090

MSDS Information

Provider	Language
H-Tyr-OMe	English
SigmaAldrich	English
ACROS	English

Methyl L-tyrosinate Usage And Synthesis

Chemical Properties	White Solid
Uses	L-Tyrosine-induced antinociception is mediated by central .delta.-opioid receptors and by the bulbo-spinal noradrenergic system.
Uses	L-Tyrosine methyl ester is used as a dehydroepiandrosterone as a sulfate acceptor
Definition	ChEBI: An L-tyrosyl ester that is the methyl ester of L-tyrosine.

Methyl L-tyrosinate Preparation Products And Raw materials

Raw materials	1H-Indole-2-carboxylic acid, 5-hydroxy-6-methoxy-, methyl ester-->Methyl L-tyrosinate hydrochloride-->L-Tyrosine hydrochloride-->methyl 2-amino-3-(3-hydroxyphenyl)propanoate-->Z-TYR-OME-->L-Tyrosine-->Methanol-->Ethanol-->Acetyl chloride-->Isopropyl alcohol-->Allyl alcohol-->2,2-Dimethoxypropane
Preparation Products	N-ME-TYR-OH

3,5-Diiodo-L-tyrosine ethyl ester hydrochloride H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH TYROSINASE Ethyl N-acetyl-L-tyrosinate hydrate CHLOROAC-TYR-OET O-METHYL-D-TYROSINE Z-HIS-TYR-TYR-OET Tribenuron methyl AC-3,5-DINITRO-TYR-OET Ethyl N-benzoyl-L-tyrosinate Methyl L-tyrosinate N-CBZ-VAL-TYR METHYL ESTER BOC-O-BENZYL-L-TYROSINE 4-NITROPHENYL ESTER Z-HIS-PHE-TYR-OET Ethyl 2-(acetylamino)-3-[3,5-diamino-4-(4-methoxyphenoxy)phenyl]propanoate Methyl acetate Z-TYR-ONP Z-TYR-OME

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