Methylprednisolone acetate

Methylprednisolone acetate Basic information
Product Name:Methylprednisolone acetate
Synonyms:depo-medrone;Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-6-methyl-, (6.alpha.,11.beta.)-;METHYLPREDNISOLONEACETATE,MICRONIZED,USP;21-Acetoxy-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione;6a-Methylprednisolone 21-acetate;DepMedalone 40;DepMedalone 80;Mepred
CAS:53-36-1
MF:C24H32O6
MW:416.51
EINECS:200-171-3
Product Categories:API;Miscellaneous Biochemicals;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Steroid and Hormone;53-36-1
Mol File:53-36-1.mol
Methylprednisolone acetate Structure
Methylprednisolone acetate Chemical Properties
Melting point 192-195°C
alpha D20 +101° (dioxane)
Boiling point 454.82°C (rough estimate)
density 1.1156 (rough estimate)
refractive index 1.4593 (estimate)
storage temp. Refrigerator
solubility Practically insoluble in water, sparingly soluble in acetone and in ethanol (96 per cent).
pka12.41±0.70(Predicted)
form neat
color White to Off-White
CAS DataBase Reference53-36-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 63-62
Safety Statements 36/37-24/25
HS Code 32041200
ToxicityLD50 oral in rat: > 10gm/kg
MSDS Information
Methylprednisolone acetate Usage And Synthesis
Chemical PropertiesOff-White Solid
UsesMethylprednisolone acetate is used as a glucocorticoid.
Uses6α-Methyl Prednisolone 21-Acetate is used as a glucocorticoid.
DefinitionChEBI: An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid.
Brand nameMedrol (Pharmacia & Upjohn).
Methylprednisolone acetate Preparation Products And Raw materials
Methylprednisolone aceponate Methylprednisolone 6alpha-Methylprednisolone sodium succinate MethylprednisoloneSuleptanate Sodium acetate 1-Methoxy-2-propyl acetate POLY(VINYL ACETATE) Prednisolone Cellulose acetate Methylprednisolone acetate ACETATE Ethyl acetate Glatiramer acetate Vinyl acetate Medroxyprogesterone Acetate Ammonium acetate Prednisolone-21-acetate 9alpha-Fluoro-16alpha-methylprednisolone acetate

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