DIETHYL DIETHYLMALONATE

DIETHYL DIETHYLMALONATE Basic information
Product Name:DIETHYL DIETHYLMALONATE
Synonyms:DIETHYLMALONIC ESTER;2,2-diethyl-malonicaciddiethylester;Diethyl 2,2-diethylmalonate;Diethyldiethylpropanedioate;Diethylmalonate diethyl ester;Diethylpropanedioicaciddiethylester;diethyl-propanedioicacidiethylester;Malonic acid, diethyl-, diethyl ester
CAS:77-25-8
MF:C11H20O4
MW:216.27
EINECS:201-016-2
Product Categories:API intermediates;Pharmaceutical Intermediates
Mol File:77-25-8.mol
DIETHYL DIETHYLMALONATE Structure
DIETHYL DIETHYLMALONATE Chemical Properties
Boiling point 228-230 °C (lit.)
density 0.99 g/mL at 25 °C (lit.)
refractive index n20/D 1.423(lit.)
Fp 202 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform, Methanol (Sparingly)
form Oil
color Clear Colourless
Specific Gravity0.988 (20/4℃)
Merck 14,3823
LogP2.463 (est)
CAS DataBase Reference77-25-8(CAS DataBase Reference)
EPA Substance Registry SystemPropanedioic acid, diethyl-, diethyl ester (77-25-8)
Safety Information
Safety Statements 24/25
WGK Germany 3
TSCA Yes
HS Code 29171900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
DIETHYL DIETHYLMALONATE Usage And Synthesis
Chemical Propertiesclear colorless liquid
Usesmanufacture of barbiturates.
UsesDiethyl Diethylmalonate is an intermediate in the synthesis of Barbital (B118500), a prototype of the barbiturate hypnotics.
Synthesis Reference(s)Journal of the American Chemical Society, 64, p. 578, 1942 DOI: 10.1021/ja01255a034
DIETHYL DIETHYLMALONATE Preparation Products And Raw materials
DIETHYL DIPENTYLMALONATE Diethyl dibutylmalonate Diethyl ethyl(1-methylbutyl)malonate ALLYL-1-METHYLBUTYLDIETHYL MALONATE DIISOBUTYLMALONIC ACID DIETHYL ESTER DIETHYL ETHYL-N-AMYLMALONATE DIETHYLMALONIC ACID DIETHYL SEC-BUTYLETHYLMALONATE Diethyl ethyl(isoamyl)malonate DIETHYL DIHEPTYLMALONATE BUTYL TRIETHYL MALONATE TRIETHYL 1-CYANO-3,3,4-PENTANE-TRICARBOXYLATE DIETHYL DIETHYLMALONATE TETRAETHYL PENTANE-1,3,3,5-TETRACARBOXYLATE DIETHYL DIETHYLMALONATE (DEDEM) DIETHYL 5-OXOCYCLOOCTANE-1,1-DICARBOXYLATE DIETHYL 4-OXOCYCLOHEXANE-1,1-DICARBOXYLATE DIETHYL ETHYL N-PROPYL MALONATE

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