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| | 6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE Basic information |
| | 6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE Chemical Properties |
| Melting point | 235°C | | Boiling point | 478.66°C (rough estimate) | | density | 1.2764 (rough estimate) | | refractive index | 1.5855 (estimate) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | solubility | DMSO:84.5(Max Conc. mg/mL);246.08(Max Conc. mM)
Water:69.0(Max Conc. mg/mL);104.84(Max Conc. mM) | | form | Solid | | color | Pale Yellow to Light Yellow | | CAS DataBase Reference | 1837-57-6(CAS DataBase Reference) | | EPA Substance Registry System | Rivanol (1837-57-6) |
| | 6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE Usage And Synthesis |
| Chemical Properties | Pale-yellow crystals. Slowly soluble in 15 parts water; soluble
in 9 parts boiling water; soluble in 110 parts alcohol
(22C). Solutions are yellow, fluorescent, and stable
to boiling. | | Originator | Rivanol,Sopharma | | Uses | 2-Ethoxy-6,9-diaminoacridine Lactate is used in treating purulent-necrotic wounds of hooves in cattle. | | Uses | Bactericide, surgical antisepsis, preparation of
pure γ-globulin. | | Definition | ChEBI: Acrinol is an organic molecular entity. | | Manufacturing Process | A mixture of 250 parts by volume of ethylene glycol, 50 parts by weight of 6-
nitro-9-chloro-2-ethoxyacridine (obtained by reaction of 52 parts by weight of
30 nitro-4-ethoxy-diphenylamine-6-carboxylic acid with phosphorous
oxychloride), 10 parts by weight of ammonium chloride, and 11 parts by
weight of urea were heated to 170°C and stirred for 1 hour at 170°-175°C.
Subsequently, the whole was cooled to 100°C, the reaction mixture was
introduced into 1000 parts by volume of water, rendered acidic to Congo
paper by means of hydrochloric acid and the 6-nitro-9-amino-2-ethoxyacridine
precipitated was filtered off. By reduction iron according to Bechamp, 6,9-
diamino-2-ethoxy-acridine hydrochloride was obtained with yield of 83% as
the yellow needles. The base was prepared by adding an equivalent of NaOH.
MP: 124°C.
In practice it is usually used as lactate. | | Therapeutic Function | Antiseptic, Antibacterial | | Safety Profile | Poison by
subcutaneous, intraperitoneal, and
intravenous routes. Experimental
reproductive effects. An antiseptic. When
heated to decomposition it emits toxic
fumes of NOx. |
| | 6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE Preparation Products And Raw materials |
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