2,3-O-Isopropylidene-D-ribonic gamma-lactone

2,3-O-Isopropylidene-D-ribonic gamma-lactone Basic information
Product Name:2,3-O-Isopropylidene-D-ribonic gamma-lactone
Synonyms:2,3-O-ISOPROPYLIDENE-D-RIBONIC ACID GAMMA LACTONE;2,3-O-ISOPROPYLIDENE-D-RIBONIC GAMMA-LACTONE;2,3-O-ISOPROPYLIDENE-D-RIBONO-1,4-LACTONE;2,3-ISOPROPYLIDENE-D-RIBONOLACTONE;ISOPROPYLIDENE-D-RIBONOLACTONE;2,3-o-isopropylidene-d-ribonic γ-lactone;D-Ribonic acid, 2,3-O-(1-methylethylidene)-, .gamma.-lactone;D-(2,3-Isopropylidene)lyxono-1,4-lactone
CAS:30725-00-9
MF:C8H12O5
MW:188.18
EINECS:
Product Categories:Carbohydrates & Derivatives;13C & 2H Sugars
Mol File:30725-00-9.mol
2,3-O-Isopropylidene-D-ribonic gamma-lactone Structure
2,3-O-Isopropylidene-D-ribonic gamma-lactone Chemical Properties
Melting point 135-139 °C
alpha -68.5 º (c=2, Pyridine)
Boiling point 243.17°C (rough estimate)
density 1.2069 (rough estimate)
refractive index 1.4348 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in methanol at 50mg/ml, acetone, dichloromethane, ethyl Acetate.
form Powder
pka13.68±0.10(Predicted)
color White to Off-white
optical activity[α]20/D 69°, c = 2 in pyridine
Water Solubility soluble
BRN 10090
CAS DataBase Reference30725-00-9(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
HS Code 29322090
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
2,3-O-Isopropylidene-D-ribonic gamma-lactone Usage And Synthesis
Description2,3-Isopropylidene-D-ribonolactone is a building block. It has been used in the stereocontrolled synthesis of the carbohydrates 6-epi-trehazolin and 6-epi-trehalamine.
Chemical PropertiesWhite Crystalline Solid
Uses2,3-O-Isopropylidene-D-ribonic acid-1,4-lactone is used for the synthesis of C-nucleosides, prostanoids and GABA analogs via homochiral 2-piperidones. It is the starting material for the preparation of biochemical compounds including C-nucleosides, such as neplanocin A, and GABA analogs, via homochiral 2-piperidones.
2,3-O-Isopropylidene-D-ribonic gamma-lactone Preparation Products And Raw materials
Raw materialsD-XYLONO-1,4-LACTONE-->D(+)-Ribonic acid gamma-lactone-->2,2-Dimethoxypropane
Preparation Products5-BROMO-5-DEOXY-2,3-O-ISOPROPYLIDENE-D-RIBONOLACTONE
ETHYL 2-ETHOXYPROPIONATE 2-ISOPROPOXYPROPANOIC ACID 2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde D-ERYTHRONOLACTONE 5-O-(TERT-BUTYLDIMETHYLSILYL)-2,3-O-ISOPROPYLIDENE-D-RIBONIC ACID GAMMA-LACTONE D-LYXONO-1,4-LACTONE Isoproterenol ETHYL (R)-(-)-2-METHOXYPROPIONATE 2,3-CYCLOHEXYLIDENE-D-RIBONIC ACID GAMMA-LACTONE Heptafluoroisopropyl iodide 2,3-O-Isopropylidene-D-ribonic gamma-lactone (S)-3-Hydroxy-gamma-butyrolactone 2,3-O-ISOPROPYLIDENE-D-ERYTHRONOLACTONE (R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER D(+)-Ribonic acid gamma-lactone 1,3,6-TRIOXACYCLOOCTANE 5-Deoxy-D-ribose 2,2-Dimethyl-1,3-Dioxolane-4-Carboxylic Acid

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