DL-3-Hydroxybutyric acid sodium salt

DL-3-Hydroxybutyric acid sodium salt Basic information
Product Name:DL-3-Hydroxybutyric acid sodium salt
Synonyms:(+/-)-3-HYDROXYBUTYRIC ACID SODIUM SALT;3-HYDROXYBUTYRIC ACID SODIUM SALT;DL-B-HYDROXYBUTYRIC ACID SODIUM*CRYSTALL INE;B-HydroxybutyricAcidSodiumSalt;Butanoic acid, 3-hydroxy-, monosodium salt;dl-β-hydroxybutyric acid sodium salt;DL-B-HYDROXYBUTYRICACIDSODIUMSALT;Sodium 3-hydroxyburyrate
CAS:150-83-4
MF:C4H7NaO3
MW:126.09
EINECS:205-774-5
Product Categories:Aliphatics;150-83-4
Mol File:150-83-4.mol
DL-3-Hydroxybutyric acid sodium salt Structure
DL-3-Hydroxybutyric acid sodium salt Chemical Properties
Melting point 167-170 °C
storage temp. 2-8°C
solubility Methanol (Slightly, Sonicated), Water (Slightly)
form Crystalline Powder
color White
Sensitive Hygroscopic
BRN 4824866
Stability:Hygroscopic
InChIInChI=1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1
InChIKeyNBPUSGBJDWCHKC-UHFFFAOYSA-M
SMILESC(O)(C)CC([O-])=O.[Na+]
CAS DataBase Reference150-83-4(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
RTECS 205-774-5
3-10
HS Code 29181990
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
DL-3-Hydroxybutyric acid sodium salt Usage And Synthesis
Chemical Propertieswhite crystalline powder
UsesOptically active 3-hydroxybutyric acids are key intermediates of the biosynthesis and metabolism of fatty acids and exist widely in biological systems.
UsesDL-3-Hydroxybutyric acid sodium salt has been used in a study to understand the effect of butyrate on fibroblast growth factor 21 (FGF21), which is involved in fatty acid ?-oxidation in liver. It may be used in the preparation of poly(3-hydroxybutyrate).
DefinitionChEBI: An organic sodium salt resulting from the replacement of the proton from the carboxy group of 3-hydroxybutyric acid by a sodium ion.
ApplicationDL-β-Hydroxybutyric acid sodium salt has been used:
as a standard for quantifying blood plasma and milk β-hydroxybutyric acid in Danish Jersey cows.
to investigate its anticonvulsant effects in epilepsy induced rats.
to induce hyperketonemia in Holstein dairy cows.
Biological FunctionsNeuroprotective compound in experimental models of neurodegenerative diseases. Shown to be oxidized as an energetic substrate in the brain during starvation. May inhibit brain glucose oxidation, which may account for the suppression of hepatic glucose production observed after administration of ketone bodies in humans.
Biochem/physiol Actionsβ-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD+, measured fluorimetrically. A high plasma level of β-hydroxybutyric acid is implicated in diabetic ketoacidosis. It traverses the blood-brain barrier as a monocarboxylic acid. β-Hydroxybutyric acid may play a protective role in dopaminergic neurodegeneration in Parkinson′s disease model. β-Hydroxybutyric acid is a ligand for G protein-coupled receptor(GPR109A) and favors inhibition of secretion, transcription and translation of growth hormone (GH) and prolactin (PRL) gene in cow anterior pituitary cells (DCAPCs).
DL-3-Hydroxybutyric acid sodium salt Preparation Products And Raw materials
Raw materialsSodium hydroxide-->Hydrochloric acid-->Ethyl acetate-->Methanol-->Potassium hydroxide-->Sodium borohydride-->Methyl acetoacetate-->Crotonic acid
PHENOLPHTHALEIN GLUCURONIC ACID SODIUM GLUCOHEPTONATE disodium epoxysuccinate BISMUTH SODIUM TARTRATE Isocitric acid trisodium salt NIGERICIN SODIUM SALT [R-(R*,R*)]-tartaric acid, sodium salt SODIUM DIHYDROXYTARTRATE 1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL 3-GLUCURONIDE SODIUM SALT UDPGA TRISODIUM SALT DL-3-Hydroxybutyric acid sodium salt 1-NAPHTHYL-B-D-GLUCURONIDE, SODIUM SALT Sodium citrate Sodium malate Salinomycin 1,3,5[10]-ESTRATRIENE-3,16ALPHA,17BETA-TRIOL 3-GLUCURONIDE SODIUM SALT 2-NAPHTHYL-BETA-D-GLUCURONIC ACID, SODIUM SALT Disodium citrate

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.