|
| | Diethyl fumarate Basic information |
| | Diethyl fumarate Chemical Properties |
| Melting point | 1-2 °C (lit.) | | Boiling point | 218-219 °C (lit.) | | density | 1.052 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.44(lit.) | | Fp | 197 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | 3.1g/l | | form | Liquid | | color | Clear colorless to slightly yellow | | Water Solubility | immiscible | | BRN | 775347 | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, acids, bases, reducing agents. | | InChIKey | IEPRKVQEAMIZSS-AATRIKPKSA-N | | LogP | 2.200 (est) | | CAS DataBase Reference | 623-91-6(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Butenedioic acid (E)-, diethyl ester(623-91-6) | | EPA Substance Registry System | Diethyl fumarate (623-91-6) |
| | Diethyl fumarate Usage And Synthesis |
| Chemical Properties | colourless liquid | | Uses | It is used as a pesticide or comonomer
for the production of polystyrene. | | Uses | Diethyl fumarate is unsaturated polyester resins are used in applications, such as reinforced glass fiber for boats, piping, bathtubs, roof panels, etc., and as protective coatings, finishes, and lacquers. | | Uses | Diethyl Fumarate is a reagent in the preparation of chiral hydroisoindolines via Diels-Alder cycloaddition which are potent, brain-penetrant, human neurokinin-1 receptor antagonists. | | Production Methods | Diethyl fumarate is manufactured via esterification of ethanol
with fumaric acid. | | Definition | ChEBI: A dieter obtained by the formal condensation of fumaric acid with ethanol. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 52, p. 323, 1987 DOI: 10.1021/jo00378a045
Tetrahedron Letters, 28, p. 6649, 1987 DOI: 10.1016/S0040-4039(00)96936-3 | | Purification Methods | Wash the fumarate with aqueous 5% Na2CO3, then with saturated CaCl2 solution, dry with CaCl2 and distil it. [Beilstein 2 IV 2207.] |
| | Diethyl fumarate Preparation Products And Raw materials |
|
