2-CHLOROQUINOLINE-4-CARBOXYLIC ACID

2-CHLOROQUINOLINE-4-CARBOXYLIC ACID Basic information

Product Name:	2-CHLOROQUINOLINE-4-CARBOXYLIC ACID
Synonyms:	AKOS BB-6908;A-CHLORO CINCHONINIC ACID;2-CHLORO-4-CARBOXY QUINOLINE;2-CHLOROQUINOLINE-4-CARBOXYLIC ACID;2-chloroquinazoline-4-carboxylic acid ethyl ester;4-Quinolinecarboxylic acid, 2-chloro-;Nsc25654;2-Chlorocinchoninic acid
CAS:	5467-57-2
MF:	C10H6ClNO2
MW:	207.61
EINECS:
Product Categories:	CHIRAL CHEMICALS;Quinoline;Quinoline series;Carboxylic Acids;Carboxylic Acids;Quinolines, Isoquinolines & Quinoxalines;Quinolines, Isoquinolines & Quinoxalines;Haloquinolines;Quinolines
Mol File:	5467-57-2.mol

2-CHLOROQUINOLINE-4-CARBOXYLIC ACID Chemical Properties

Melting point	244 °C
Boiling point	368.7±22.0 °C(Predicted)
density	1.469±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to crystal
pka	2.17±0.10(Predicted)
color	White to Orange to Green
CAS DataBase Reference	5467-57-2(CAS DataBase Reference)

Safety Information

MSDS Information

2-CHLOROQUINOLINE-4-CARBOXYLIC ACID Usage And Synthesis

Uses	2-Chloroquinoline-4-carboxylic Acid is an intermediate used to prepare dimethyl(naphthalenecarbonyl)aminobenzoic acids as potent and selective EP4 antagonists.

2-CHLOROQUINOLINE-4-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials	4-Quinolinecarboxylic acid, 1-oxide-->4-BROMO-2-CHLOROQUINOLINE-->2-Hydroxy-4-quinolincarboxylic acid-->Formyl acetate-->4-Methylquinoline 1-oxide-->4-Quinolinecarboxylic acid, 2-chloro-, ethyl ester-->Isatin
Preparation Products	QUINOLINE-4-CARBOXYLIC ACID-->2-(4-FLUORO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID

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