3-Fluoropyridine

3-Fluoropyridine Basic information
Product Name:3-Fluoropyridine
Synonyms:Pyridine, 3-fluoro-;3-FLUOROPYRIDINE;3-Fluoroypyridine;3-FLUOROPYRIDINE 98% (GC);3-Fluoropyridine,98%;3-Fluoropyridine 98%;3-Fluoropyridine, 99% 1GR;3-Fluoropyridine,99%
CAS:372-47-4
MF:C5H4FN
MW:97.09
EINECS:206-755-4
Product Categories:Building Blocks;Chemical Synthesis;Fluorinated Building Blocks;Heterocyclic Building Blocks;Heterocyclic Fluorinated Building Blocks;Other Fluorinated Heterocycles;Pyridine;Pyridines, Pyrimidines, Purines and Pteredines;Pyridine series;Halides;Pyridines;Pyridines derivates;Fluorine series;alkyl Fluorine;Fluorin-contained pyridine series;Fluoropyridines;Halopyridines;C5;Heterocyclic Building Blocks;bc0001
Mol File:372-47-4.mol
3-Fluoropyridine Structure
3-Fluoropyridine Chemical Properties
Melting point 251-254°C (dec.)
Boiling point 107-108 °C (lit.)
density 1.13 g/mL at 25 °C (lit.)
refractive index n20/D 1.472(lit.)
Fp 56 °F
storage temp. Inert atmosphere,Room Temperature
form Liquid
pkapK1:2.97(+1) (25°C)
Specific Gravity1.130
color Clear yellow
BRN 105702
InChIKeyCELKOWQJPVJKIL-UHFFFAOYSA-N
CAS DataBase Reference372-47-4(CAS DataBase Reference)
NIST Chemistry Reference3-F-pyridine(372-47-4)
Safety Information
Hazard Codes F,Xi,Xn
Risk Statements 11-36/37/38-20/21/22
Safety Statements 16-26-36/37/39-33-7/9
RIDADR UN 1993 3/PG 2
WGK Germany 3
Hazard Note Flammable/Irritant
HazardClass 3
PackingGroup II
HS Code 29333990
MSDS Information
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3-Fluoropyridine Usage And Synthesis
Chemical Propertiesclear, colorless to yellow liquid.
Uses3-Fluoropyridine was used in the synthesis of 3-halopyridin-4-yl-boronic acids and esters.
PreparationA combination of CsF and HF provides a very reactive fluoride source and has shown faint promise with 3-chloropyridine giving 3-fluoropyridine in a very low yield.
synthesis of 3-Fluoropyridine
General Description3-Fluoropyridine is oxidized to corresponding N-oxides, which on treatment with hot acetic anhydride and hydrolysis yields 3-halo-2-pyridones. Microwave spectrum of 3-fluoropyridine has been investigated in the frequency range of 8-18GHz at dry ice temperature. Deprotonation of 3-fluoropyridine with Bu3MgLi in THF at -10°C has been studied.
2-Amino-3-fluoropyridine 2-Fluoropyridine 2-Chloro-3-fluoropyridine 3-Chloro-2,4,5,6-tetrafluoropyridine 2-Chloro-3-cyanopyridine 2,3,5,6-Tetrafluoropyridine 3-FLUORO-4-NITROPYRIDINE-N-OXIDE 4-Methylpyridine Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 3-Aminopyridine 4-AMINO-3-CHLORO-2,5,6-TRIFLUOROPYRIDINE 2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE 3-Fluoropyridine Flupirtine 2-BROMO-4-AMINO-5-FLUOROPYRIDINE 3-FLUOROQUINOLINE 4-Bromo-2,3,5,6-tetrafluoropyridine 5-FLUOROPYRIDINE-2-BORONIC ACID

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