Fenpyroximate

Fenpyroximate Basic information
Product Name:Fenpyroximate
Synonyms:4-[[[[(1,3-Dimethyl-5-phenoxy-1H-pyrazol-4-yl)methylene]amino]oxy]methyl]-benzoic acid 1,1-dimethylethyl ester;tert-butyl (e)-4-(((((1,3-dimethyl-5-phenoxy-1h-pyrazol-4-yl)methylene)amino)oxy)methyl)benzoate;PAMANRIN;ORTUS;1,1-dimethylethylester,(e)-)methyl);4-(((((1,3-dimethyl-5-phenoxy-1h-pyrazol-4-yl)methylene)amino)oxy)methyl)-,1,1-dimethylethylester,benzoicaci;benzoicacid,4-(((((1,3-dimethyl-5-phenoxy-1h-pyrazol-4-yl)methylene)amino)oxy;nni850
CAS:134098-61-6
MF:C24H27N3O4
MW:421.49
EINECS:
Product Categories:
Mol File:134098-61-6.mol
Fenpyroximate Structure
Fenpyroximate Chemical Properties
Melting point 101.1-102.4°
Boiling point 546.2±60.0 °C(Predicted)
density 1.25g/cm3
storage temp. Store at -20°C
Water Solubility Insoluble in water
solubility Chloroform: Slightly soluble,Methanol: Slightly soluble
pka1.58±0.10(Predicted)
form powder to crystal
color White to Light yellow to Light orange
Stability:Light Sensitive
LogP6.443 (est)
CAS DataBase Reference134098-61-6(CAS DataBase Reference)
EPA Substance Registry SystemFenpyroximate (134098-61-6)
Safety Information
RIDADR UN3082 (liquid)
HS Code 29331990
Hazardous Substances Data134098-61-6(Hazardous Substances Data)
ToxicityLD50 in male, female rats (mg/kg): 480, 245 orally; >2000, >2000 dermally; LC50 (48hr) in carp: 6.1 mg/l; LC50 (3hr) in daphnia pulex: 85 mg/l (Konno)
MSDS Information
Fenpyroximate Usage And Synthesis
UsesAcaricide.
DefinitionChEBI: Fenpyroximate is a pyrazole acaricide and a tert-butyl ester. It has a role as a mitochondrial NADH:ubiquinone reductase inhibitor. It derives from a hydride of a 1H-pyrazole.
Agricultural UsesAcaricide, Miticide, Insecticide: Used to control spider mites in greenhouses.
Trade nameAKARI®; HOE® 555-02A; NNI®-850; SEQUEL®
Metabolic pathwayWhen fenpyroximate is administered orally to rats, radiocarbons from 14C-fenpyroximate are rapidly and almost completely excreted in the urine and feces within 72 h, and fenyproximate seems to be metabolized via oxidation of the tert-butyl group and methyl group at the 3-position in the pyrazole ring, p- hydroxylation in the phenoxy moiety, N-demethylation, hydrolysis of the tert-butyl ester, cleavage of the oxime ether bond, and/or E/Z isomerization. In soils, 12 degradation products are identified, and in sterilized soils the degradation of fenpyroximate and CO2, evolution are negligible. Fenpyroximate degrades through hydrolysis of tert-butyl ester, isomerization or cleavage of the oxime ether, N-demethylation, oxidation of the methyl group at the 3-position on the pyrazole ring, and hydroxylation of the phenoxy ring, and is finally mineralized to CO2 and/or bound to soil organic matter.
Methylene Chloride Dacthal phenoxybenzamine Methylene Blue ETHANE tert-Butyl peroxybenzoate tert-Butanol p-Anisic acid Isobutyl chloroformate Dimethyl sulfoxide Diethoxydimethylsilane 4,4'-Diphenylmethane diisocyanate 3,5-Dimethylbenzoic acid Dimethyl disulfide Dimethyl ether Dimethyl carbonate Butyl benzoate Dimethyl sulfate

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