2'-C-Methyluridine

2'-C-Methyluridine Basic information
Applications
Product Name:2'-C-Methyluridine
Synonyms:1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione;Uridine, 2'-C-Methyl-;2'-C-Methyl-1-β-D-ribofuranosyluracil;2'-C-Methyluridine;1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione;1-((2R,3R,4R,5R)-TETRAHYDRO-3,4-DIHYDROXY-5-(HYDROXYMETHYL)-3-METHYLFURAN-2-YL)PYRIMIDINE-2,4(1H,3H)-DIONE;EOS-61181;1-(2-C-Methyl-β-D-ribofuranosyl)uracil
CAS:31448-54-1
MF:C10H14N2O6
MW:258.23
EINECS:
Product Categories:
Mol File:31448-54-1.mol
2'-C-Methyluridine Structure
2'-C-Methyluridine Chemical Properties
Melting point 110-112 °C
density 1.572
storage temp. 2-8°C
form powder to crystal
pka9.39±0.10(Predicted)
color White to Almost white
Safety Information
HS Code 2940.00.6000
MSDS Information
2'-C-Methyluridine Usage And Synthesis
Applications

There are two main applications of 2'-C-methyluridine, which are targeted at hepatitis C and leukemia.2′-C-methyluridine is one of the key intermediates in the synthesis of nucleoside anti-hepatitis C and anti-leukemia drugs.

UsesA 2’C-Me branched C-nucleoside that shows HCV polymerase inhibitory activity.
UsesA 2’-C-Me branched C-nucleoside that shows HCV polymerase inhibitory activity.
2'-C-Methyluridine Preparation Products And Raw materials
Raw materials2'-C-Methyl-, 2',3',5'-tribenzoateuridine
Uridine Tiglic aldehyde Floxuridine 2,6-Dimethylphenol Doxifluridine uridine diphosphate glucose {= UDP-glucose} 2'-C-Methyluridine Trifluridine 2,6-Lutidine L-Uridine 1-beta-D-Arabinofuranosyluracil

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