ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyrimidines Methylpyrimidine 2,4-dichloro-6-(trifluoromethyl)pyrimidine

2,4-dichloro-6-(trifluoromethyl)pyrimidine

2,4-dichloro-6-(trifluoromethyl)pyrimidine Basic information
Product Name:2,4-dichloro-6-(trifluoromethyl)pyrimidine
Synonyms:2,4-dichloro-6-(trifluoromethyl)pyrimidine;2,4-Dichloro-6-(trifluoromethyl)-1,3-diazine;PyriMidine, 2,4-dichloro-6-(trifluoroMethyl)-;4-Dichloro-6-(trifluoromethyl)pyrimidine;2,4-Dichloro-6-(trifluoromethyl)pyrimidine 98%;2,4-dichloro-6-(trifluoromethyl)pyrimidine ISO 9001：2015 REACH
CAS:16097-64-6
MF:C5HCl2F3N2
MW:216.98
EINECS:
Product Categories:Fluorine series;pharmacetical
Mol File:16097-64-6.mol
2,4-dichloro-6-(trifluoromethyl)pyrimidine Structure
2,4-dichloro-6-(trifluoromethyl)pyrimidine Chemical Properties
Melting point -48--46 °C
Boiling point 37-38 °C(Press: 0.7 Torr)
density 1.589
refractive index 1.4640
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form Liquid
pka-7.56±0.32(Predicted)
color Pale yellow
Safety Information
HS Code 29335990
MSDS Information
2,4-dichloro-6-(trifluoromethyl)pyrimidine Usage And Synthesis
Uses2,4-Dichloro-6-trifluoromethylpyrimidine is a useful synthetic intermediate. It can be used to synthesize 2,4-diaminopyrimidines derivatives that show antiplasmodial activities.
Synthesis Reference(s)Journal of Heterocyclic Chemistry, 24, p. 1243, 1987 DOI: 10.1002/jhet.5570240502
2,4-dichloro-6-(trifluoromethyl)pyrimidine Preparation Products And Raw materials
Preparation Products2-Chloro-6-(trifluoromethyl)pyrimidin-4-amine-->2-Chloro-4-ethoxy-6-(trifluoroMethyl)pyriMidine
2,4-Dichloro-5-trifluoromethylpyrimidine 2,4-DICHLORO-6-(TRIFLUOROMETHYL)PYRIMIDIN-5-AMINE 4-Chloro-6-trifluoromethylpyrimidine 2,4-DICHLORO-5-NITRO-6-(TRIFLUOROMETHYL)PYRIMIDINE 2,4-dichloro-6-(trifluoromethyl)pyrimidine
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