MAF

MAF Basic information
Product Name:MAF
Synonyms:Ferric methylarsonate;good quality 99.5% MAF with lowest price;MAF 5F-MDMB-2201 methoxyaceylfentanyl;MAF power;MAF;IFN-γ human;Immune Interferon;T cell interferon
CAS:101365-54-2
MF:C22H29ClN2O2
MW:388.94
EINECS:
Product Categories:pharmaceutical intermediates;research chemical;Chemical and pharmaceutical intermediates;Medical research;pharmaceutical intermediate or chemical research
Mol File:Mol File
MAF Structure
MAF Chemical Properties
storage temp. -20°C
solubility DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 20 mg/ml; Methanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form A neat solid
Stability:Hygroscopic
Safety Information
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
MSDS Information
MAF Usage And Synthesis
UsesIFN-γ (interferon γ)-human has been used for the generation of inflammatory M1 cells from human monocytic cell line, THP1.
General DescriptionIFN-γ (interferon γ) is an acid-labile glycosylated interferon produced by CD4 and CD8 T lymphocytes as well as activated NK (natural killer) cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC (major histocompatibility complex) proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. The gene is mapped to human chromosome 12q15. Human IFN-γ is species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.7kDa protein containing 143 amino acid residues.
Biochem/physiol ActionsIFN-γ (interferon γ) signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. It can suppress the generation of anti-inflammatory cytokines and enhance the secretion of proinflammatory cytokines. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK (natural killer) cells and neutrophils. It is responsible for tumor rejection and is capable of killing tumor cells by autophagy or apoptosis. IFN-γ is also involved in Hepatitis E virus disease pathogenesis.
MAF Preparation Products And Raw materials
HDMP-28 BB-22 2,3,5,6-TETRAMETHYL-1,4-PHENYLENEDIAMINE EG2201 Trenbolone cyclohexylmethylcarbonate 4-CPRC 4-Chloro-3-methylphenol MAF 3-hydroxyphencyclidine MMB-2201 N-ethyl-p-methoxy-alpha-methylphenethylamine Diclazepam Dibutylone crystals AMB-CHMINACA MMBC 2-(3-fluorophenyl)-3-methylmorpholine(3-fluorophenmetrazine)(3-FPM) Cyclohexanone,2-(methylamino)-2-phenyl-, hydrochloride (1:1) METHYLARSONIC ACID

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