ChemicalBook Product Catalog Biochemical Engineering Condensing agent DEPBT

DEPBT

DEPBT Basic information
Product Name:DEPBT
Synonyms:DEPBT;DIETHYL-(4-OXO-3H-1,2,3-BENZOTRIAZIN-3-YL)PHOSPHATE;DIETHYL 3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZIN-3-YL PHOSPHATE;3-DIETHOXYPHOSPHORYL-1,2,3-BENZOTRIAZIN-4(3H)-ONE;3-(Diethoxyphosphoryloxy)-1,2,3-benzotrizin-4(3H)-one;3-(Diethoxy-phosphoryloxy)-1,2,3-benzo[d]triazin-4(3H)-one;Phosphoricacid, diethyl 4-oxo-1,2,3-benzotriazin-3-yl ester;3-(Diethoxy-phosphoryloxy)-3H-benzo[δ][1,2,3]triazin-4-one
CAS:165534-43-0
MF:C11H14N3O5P
MW:299.22
EINECS:628-030-5
Product Categories:Antibiotics;Peptide Coupling Reagents;Coupling Reagent;Biochemistry;Condensation & Active Esterification;Coupling Reactions (Peptide Synthesis);Peptide Synthesis;Synthetic Organic Chemistry;Peptide;Building Blocks;Heterocyclic Building Blocks;Triazines
Mol File:165534-43-0.mol
DEPBT Structure
DEPBT Chemical Properties
Melting point 75-77°C
Boiling point 382.1±25.0 °C(Predicted)
density 1.45±0.1 g/cm3(Predicted)
storage temp. Store at +2°C to +8°C.
solubility almost transparency in Ethylacetate
form Powder
color White
InChIKeyAJDPNPAGZMZOMN-UHFFFAOYSA-N
CAS DataBase Reference165534-43-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HS Code 29339990
MSDS Information
DEPBT Usage And Synthesis
Chemical PropertiesWhite solid
UsesDEPBT is a peptide coupling reagent used in peptide synthesis. It shows remarkable resistance to racemization.
General Description3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one (DEPBT) is a coupling reagent that facilitates amide bond formation and also resists racemization. It has been shown to be more effective than phosphonium and uronium coupling reagents.
DEPBT Preparation Products And Raw materials
Raw materials3-Hydroxy-1,2,3-benzotriazin-4(3H)-one-->Diethyl phosphite-->Diethyl chlorophosphate
Preparation Products1H-INDOL-1-AMINE
Diphenylphosphoryl azide Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate 5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate TSTU Bis(2-oxo-3-oxazolidinyl)phosphinic chloride Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate 1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate 6-Chloro-1-hydroxibenzotriazol Ethoxyamine hydrochloride DIETHOXYMETHANE Ethoxyquin 1,2,3-BENZOTRIAZIN-4(3H)-ONE DEPBT 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one Ethoxyethyne
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