BOC-11-AMINOUNDECANOIC ACID

BOC-11-AMINOUNDECANOIC ACID Basic information

Product Name:	BOC-11-AMINOUNDECANOIC ACID
Synonyms:	BOC-11-AMINOUNDECANOIC ACID;BOC-11-AMINOUNDECYLIC ACID;BOC-11-AUN-OH;BOC-NH-(CH2)10-COOH;11-(BOC-AMINO)-UNDECANOIC ACID;T-BUTOXYCARBONYL-11-AMINOUNDECANOIC ACID;T-BUTOXYCARBONYL-11-AMINOUNDECYLIC ACID;N-TERT-BUTYLOXYCARBONYL-11-AMINO-UNDECANOIC ACID
CAS:	10436-25-6
MF:	C16H31NO4
MW:	301.42
EINECS:
Product Categories:	Amino Acids
Mol File:	10436-25-6.mol

BOC-11-AMINOUNDECANOIC ACID Chemical Properties

Melting point	67-68 °C
Boiling point	441.9±18.0 °C(Predicted)
density	1.006±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	soluble in Methanol
pka	4.78±0.10(Predicted)
form	powder to crystal
color	White to Almost white
BRN	1975656
CAS DataBase Reference	10436-25-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	22-24/25
WGK Germany	3
HS Code	2924.19.8000
HazardClass	IRRITANT

MSDS Information

Provider	Language
SigmaAldrich	English

BOC-11-AMINOUNDECANOIC ACID Usage And Synthesis

Description

Boc-11-aminoundecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Properties

White powder

BOC-11-AMINOUNDECANOIC ACID Preparation Products And Raw materials

Preparation Products

Undecanoic acid, 11-[[(1,1-dimethylethoxy)carbonyl]amino]-, 2,5-dioxo-1-pyrrolidinyl ester

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BOC-11-AMINOUNDECANOIC ACID

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