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| | 8-AZAGUANINE Basic information |
| Product Name: | 8-AZAGUANINE | | Synonyms: | 2-Amino-6-hydroxy-8-azapurine, 2-Amino-6-oxy-8-azapurine, Guanazolo;5-aMino-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyriMidin-7-one;5-AMino-1H-[1,2,3]triazolo[4,5-d]pyriMidin-7(6H)-one;5-aMino-3H-[1,2,3]triazolo[4,5-d]pyriMidin-7(6H)-one;8-Azaguanine ,99%;8-Azaguanine,2-Amino-6-hydroxy-8-azapurine, 2-Amino-6-oxy-8-azapurine, 8-AzaG, Guanazolo;7H-1,2,3-Triazolo[4,5-d]pyriMidin-7-one, 5-aMino-3,6-dihydro-;5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL | | CAS: | 134-58-7 | | MF: | C4H4N6O | | MW: | 152.11 | | EINECS: | 205-148-1 | | Product Categories: | Nucleic acids;Pharmaceutical Raw Materials;Pyridines, Pyrimidines, Purines and Pteredines;Biochemistry;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents | | Mol File: | 134-58-7.mol |  |
| | 8-AZAGUANINE Chemical Properties |
| Melting point | >300 °C(lit.) | | Boiling point | 274.55°C (rough estimate) | | density | 1.5579 (rough estimate) | | refractive index | 2.3000 (estimate) | | storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | solubility | DMSO (Slightly) | | pKa | 6.75±0.20(Predicted) | | form | lyophilized powder | | Merck | 896 | | InChIKey | LPXQRXLUHJKZIE-UHFFFAOYSA-N | | CAS DataBase Reference | 134-58-7(CAS DataBase Reference) | | NIST Chemistry Reference | 8-Azaguanine(134-58-7) | | EPA Substance Registry System | 8-Azaguanine (134-58-7) |
| Hazard Codes | Xn | | Risk Statements | 22 | | Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | XZ6157000 | | F | 10-23 | | HS Code | 29335990 | | Toxicity | LD50 oral in mouse: 1500mg/kg |
| | 8-AZAGUANINE Usage And Synthesis |
| Chemical Properties | yellow powder | | Uses | Antineoplastic;Purine antimetabolite | | Uses | 8-Azaguanine, is a purine analogue which shows antineoplastic activity. | | Definition | ChEBI: A triazolopyrimidine that consists of 3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing amino and oxo substituents at positions 5 and 7 respectively. | | Hazard | Mitotoic poison. | | Purification Methods | Dissolve it in hot M NH4OH, filter, and cool. Recrystallise it, and wash it with water, then dry it in a vacuum. [Beilstein 26 III/IV 4171.] |
| | 8-AZAGUANINE Preparation Products And Raw materials |
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