2-Nitroethanol

2-Nitroethanol Basic information
Product Name:2-Nitroethanol
Synonyms:2-nitro-ethano;beta-nitroalcohol;beta-Nitroethanol;beta-Nitroethyl alcohol;1-nitro-2-hydroxyethane;2-Nitroethanol, 85% (Assay);nitroethanol;2-Nitroethanol, pract., 85%
CAS:625-48-9
MF:C2H5NO3
MW:91.07
EINECS:210-895-1
Product Categories:Alcohols;C2 to C6;Miscellaneous;Oxygen Compounds
Mol File:625-48-9.mol
2-Nitroethanol Structure
2-Nitroethanol Chemical Properties
Melting point -80 °C (lit.)
Boiling point 194 °C/765 mmHg (lit.)
density 1.27 g/mL at 25 °C (lit.)
refractive index n20/D 1.445(lit.)
Fp >230 °F
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform, DMSO, Methanol (Sparingly)
pka8.42±0.29(Predicted)
form Liquid
color Clear yellow
BRN 1633753
CAS DataBase Reference625-48-9(CAS DataBase Reference)
NIST Chemistry ReferenceEthanol, 2-nitro-(625-48-9)
EPA Substance Registry System2-Nitroethanol (625-48-9)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS KL9370000
3
HS Code 29055910
MSDS Information
ProviderLanguage
2-Nitroethanol English
SigmaAldrich English
ALFA English
2-Nitroethanol Usage And Synthesis
Chemical PropertiesClear yellow liquid
Uses2-Nitroethanol is an aliphatic β-nitro alcohol used as an in vivo therapeutic corneoscleral crosslinking agents with higher order nitroalcohol. It also functions as a crosslinking reagent for scieral tissue cross-linking of the eye cornea for treating keratoconus and post-surgical keratectasia.
General DescriptionMobile dark brown-red liquid with a pungent odor.
Air & Water ReactionsHygroscopic. Insoluble in water.
Reactivity Profile2-Nitroethanol is incompatible with strong oxidizing agents, strong bases, acid chlorides and acid anhydrides. 2-Nitroethanol has exploded under vacuum distillation(attributed to the presence of peroxides or alkali).
Fire Hazard2-Nitroethanol is probably combustible.
2-METHYL-2-NITRO-1,3-PROPANEDIOL Ethyl nitroacetate 2-(2-NITROETHOXY)TETRAHYDROPYRAN 3-NITRO-2-BUTANOL 2-Methyl-2-nitropropan-1-ol TRICHLORONITROPROPANOL 2,2-dinitropropanol ETHYL 2-NITROPROPIONATE Dimethyl nitromalonate 1-NITROMETHYLCYCLOHEXANOL 2-Nitroethanol Tris(hydroxymethyl)nitromethane Bronopol 1-DEOXY-1-NITRO-D-MANNITOL 2-NITRO-1-BUTANOL 3-NITRO-2-PENTANOL 2-ETHYL-2-NITRO-1,3-PROPANEDIOL 3-NITRO-3-METHYL BUTANOL-2

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