DIETHYL BENZYLPHOSPHONATE

DIETHYL BENZYLPHOSPHONATE Basic information

Product Name:	DIETHYL BENZYLPHOSPHONATE
Synonyms:	(phenylmethyl)-phosphonicacidiethylester;benzyl-phosphonicacidiethylester;Benzylphosphonsαurediethylester;Diethoxyphosphonomethylbenzene;Diethyl phosphonate, benzyl-;DIETHYL BENZOPHOSPHONATE;Phenylmethanephosphonic acid diethyl ester;Diethylbenzylphosphonate, 99 %
CAS:	1080-32-6
MF:	C11H17O3P
MW:	228.22
EINECS:	214-097-4
Product Categories:	Horner-Emmons Reaction;Synthetic Organic Chemistry;Wittig & Horner-Emmons Reaction;C-C Bond Formation;Horner-Wadsworth-Emmons Reagents;Olefination
Mol File:	1080-32-6.mol

DIETHYL BENZYLPHOSPHONATE Chemical Properties

Boiling point	106-108 °C1 mm Hg(lit.)
density	1.095 g/mL at 25 °C(lit.)
refractive index	n20/D 1.497(lit.)
Fp	>230 °F
storage temp.	Sealed in dry,Room Temperature
form	Liquid
Specific Gravity	1.10
color	Clear colorless to slightly yellow
Water Solubility	Insoluble in water.
BRN	2580931
CAS DataBase Reference	1080-32-6(CAS DataBase Reference)
EPA Substance Registry System	Phosphonic acid, (phenylmethyl)-, diethyl ester (1080-32-6)

Safety Information

MSDS Information

DIETHYL BENZYLPHOSPHONATE Usage And Synthesis

Chemical Properties	CLEAR COLOURLESS TO SLIGHTLY YELLOW LIQUID
Uses	Reactant for synthesis of: ? 3,5-dihydroxy-4-isopropylstilbene for treatment of skin disorders ? Natural cytotoxic marine products of polyketide origin via intramolecular Diels-Alder reactions ? Stilbenes via on-column oxidation of vicinal diols and Horn
Uses	Diethyl benzylphosphonate is used as a reactant for synthesis of 3,5-dihydroxy-4-isopropylstilbene for treatment of skin disorders and natural cytotoxic marine products of polyketide origin via intramolecular Diels-Alder reactions. It is also used as reactant for cyclization of aryl ethers, amines and amides & for investigating the effects of functional groups on the performance of clue organic LEDs.
Uses	Reactant for synthesis of: 3,5-dihydroxy-4-isopropylstilbene for treatment of skin disorders Natural cytotoxic marine products of polyketide origin via intramolecular Diels-Alder reactions Stilbenes via on-column oxidation of vicinal diols and Horner-Emmons reactions Inhibitors of teh Wnt pathway for colon cancer repression using Wadsworth-Emmons reactions Antimalarial drug analogs against P. falciparum Reactant for: Cyclization of aryl ethers, amines, and amides Investigating the effects of functional groups on the performance of clue organic LEDs
Synthesis Reference(s)	Tetrahedron Letters, 29, p. 1513, 1988 DOI: 10.1016/S0040-4039(00)80339-1 Synthesis, p. 222, 1981 DOI: 10.1055/s-1981-29393

DIETHYL BENZYLPHOSPHONATE Preparation Products And Raw materials

Preparation Products

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