ChemicalBook Product Catalog Biochemical Engineering Biochemical Reagents (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID

(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID

(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Basic information
Product Name:(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
Synonyms:(RS)-CPP;(RS)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID;(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID;DL-CPP;(+/-)-CPP;(+/-)-CPP POTENT AND SELECTIVE;2-Piperazinecarboxylic acid, 4-(3-phosphonopropyl)-;2-Piperazinecarboxylic acid, 4-(3-phosphonopropyl)-, (+-)-
CAS:100828-16-8
MF:C8H17N2O5P
MW:252.2
EINECS:
Product Categories:Glutamate receptor;pharmaceutical intermediates
Mol File:100828-16-8.mol
(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Structure
(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Chemical Properties
Boiling point 546.7±60.0 °C(Predicted)
density 1.408±0.06 g/cm3(Predicted)
storage temp. Desiccate at RT
solubility H2O: 99.2 mg/mL
form solid
pka1.89±0.20(Predicted)
color white
Water Solubility Soluble to 100 mM in water
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-26-36
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Usage And Synthesis
Uses(+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid is a compound with NMDA antagonistic activity.
Synthesis Reference(s)Tetrahedron Letters, 30, p. 5193, 1989 DOI: 10.1016/S0040-4039(01)93739-6
Biological ActivityPotent NMDA antagonist. See separate isomer (3-((R)-2-Carboxypiperazin-4-yl)-propyl-1-phosphonicacid ).
Biochem/physiol ActionsPotent and selective NMDA glutamate receptor antagonist; anticonvulsant.
storageRoom temperature (desiccate)
(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID Preparation Products And Raw materials
azaleucine (+/-)-3-(2-CARBOXY-PIPERAZIN-4-YL) PROPYL-1-PHOSPHONIC ACID-[PROPYL-1,2-3H]- 2,3-Diaminopropionic acid 3-Aminopropylphosphonic acid 2-Piperazinecarboxaldehyde 2-Methylpiperazine (+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID 2-Piperazinemethanol 3-((R)-2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID,R(-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID 4-METHYLPIPERAZINE-2-CARBOXYLIC ACID PIPERAZINE-2-CARBOXYLIC ACID
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