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| | 13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2 Basic information |
| Product Name: | 13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2 | | Synonyms: | 13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2;9ALPHA-HYDROXY-11,15-DIOXO-PROST-5Z-EN-1-OIC ACID;(5Z,9α)-9-Hydroxy-11,15-dioxoprost-5-en-1-oic acid;13,14-Dihydro-15-keto-PGD2;13,14-Dihydro-15-ketoprostadlandin D2;DK-PGD2;13,14-dihydro-15-keto Prostaglandin D2 Lipid Maps MS Standard;13,14-dihydro-15-keto Prostaglandin D2 | | CAS: | 59894-07-4 | | MF: | C20H32O5 | | MW: | 352.47 | | EINECS: | | | Product Categories: | | | Mol File: | 59894-07-4.mol |  |
| | 13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2 Chemical Properties |
| Boiling point | 542.1±40.0 °C(Predicted) | | density | 1.086±0.06 g/cm3(Predicted) | | pka | 4.76±0.10(Predicted) |
| | 13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2 Usage And Synthesis |
| Description | 13,14-dihydro-15-keto Prostaglandin D2 (13,14-dihydro-15-keto PGD2) is a metabolite of PGD2 which is formed through the 15-hydroxy PGDH pathway. 13,14-dihydro-15-keto PGD2 was recently identified as a selective agonist for the CRTH2/DP2 receptor. It also inhibits ion flux in a canine colonic mucosa preparation. In humans, 13,14-dihydro-15-keto PGD2 is further metabolized to give 11β-hydroxy compounds which have also undergone β-oxidation of one or both side chains. Virtually no 13,14-dihydro-15-keto PGD2 survives intact in the urine. | | Uses | 13,14-Dihydro-15-keto-PGD2 is a metabolite of Prostaglandin D2 (CAT# P838575) and a selective CRTh2/DP2 receptor agonist. CRTh2/DP2 receptors play crucial roles in atopic dermatitis, asthma, and other inflammatory diseases. | | Definition | ChEBI: 13,14-dihydro-15-ketoprostaglandin D2 is a prostaglandins D. It has a role as a metabolite. It is functionally related to a prostaglandin D2. |
| | 13,14-DIHYDRO-15-KETO PROSTAGLANDIN D2 Preparation Products And Raw materials |
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