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| | 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Basic information |
| Product Name: | 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one | | Synonyms: | 5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE;5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one;LS 75;11H-Pyrido[2,3-b][1,4]benzodiazepine-6(5H)-one;5,11-dihydropyrido[2,3-b][1,4]benzodiazepin-6-one;5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one AK-36728;6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 1,5-dihydro-;6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,5,11-dihydro- | | CAS: | 885-70-1 | | MF: | C12H9N3O | | MW: | 211.22 | | EINECS: | 212-944-2 | | Product Categories: | | | Mol File: | 885-70-1.mol | ![5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Structure](CAS/GIF/885-70-1.gif) |
| | 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Chemical Properties |
| Melting point | 292-293℃ | | Boiling point | 336℃ | | density | 1.275 | | Fp | 157℃ | | storage temp. | Refrigerator, under inert atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | | form | Solid | | pka | 11.58±0.20(Predicted) | | color | Light Beige to Beige |
| | 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Usage And Synthesis |
| Uses | 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one, can be used in the synthesis of fluorescent pirenzepine derivatives, used as potential bitopic ligands of the Human M1 Muscarinic receptor. | | Synthesis | 
In a 1000 ml reaction flask,Add 600 ml of butanol,100 g of 2-amino-N- (2-chloropyridyl-3-yl) benzamide,2 ml of concentrated sulfuric acid,The reaction was refluxed for 3 hours at a reaction temperature of 80 ?? C,Cooled to room temperature,filter,Washed with acetone,50-60 ?? C in vacuo to give 98 g of a pale yellow solid product,Yield 98percent, purity 99percent. |
| | 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Preparation Products And Raw materials |
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