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| | (11,12-DiHETE Basic information |
| Product Name: | (11,12-DiHETE | | Synonyms: | (11,12-DiHETE;11,12-dihydroxy-5(Z),8(Z),14(Z),17(Z)-eicosatetraenoic acid;11,12-dihydroxy-5(Z),8(Z),14(Z),17(Z)-Eicosapentaenoic acid;5,8,14,17-Eicosatetraenoic acid, 11,12-dihydroxy-, (5Z,8Z,14Z,17Z)- | | CAS: | 867350-92-3 | | MF: | C20H32O4 | | MW: | 336.47 | | EINECS: | | | Product Categories: | | | Mol File: | 867350-92-3.mol |  |
| | (11,12-DiHETE Chemical Properties |
| Boiling point | 515.8±50.0 °C(Predicted) | | density | 1.040±0.06 g/cm3(Predicted) | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 0.5 mg/ml | | pka | 4.75±0.10(Predicted) |
| | (11,12-DiHETE Usage And Synthesis |
| Description | (±)11(12)-DiHETE is a dihydroxy metabolite of EPA produced by cytochrome P450-mediated epoxide formation and subsequent hydrolysis by epoxide hydrolase. Plasma levels of (±)11(12)-DiHETE are increased over baseline after an oral dose of 1008 mg EPA.1 | | Definition | ChEBI: 11,12-DiHETE is a polyunsaturated fatty acid and a hydroxy fatty acid. | | References | 1. Schuchardt, J.P., Schneider, I., Willenberg, I., et al. Increase of EPA-derived hydroxy, epoxy and dihydroxy fatty acid levels in human plasma after a single dose of long-chain omega-3 PUFA Prostaglandins Other Lipid Mediat. 109-111,23-31(2014). |
| | (11,12-DiHETE Preparation Products And Raw materials |
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