Alkannin

Alkannin Basic information
Uses
Product Name:Alkannin
Synonyms:ANCHUSIN;ALKANNIN;NSC 94524;GroMwell Root Extract;Anchusaic acid;Arnebin IV;Extra Cas, 54952-43-1;(S)-5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)-1,4-naphthoquinone
CAS:517-88-4
MF:C16H16O5
MW:288.3
EINECS:208-245-7
Product Categories:
Mol File:517-88-4.mol
Alkannin Structure
Alkannin Chemical Properties
Melting point 149°
alpha 20Cd -165° (benzene); -226° (chloroform). Also reported as -254 ± 7° (chloroform) (Toribara)
Boiling point 567.4±50.0 °C(Predicted)
density 1.373±0.06 g/cm3(Predicted)
storage temp. -20°C, protect from light
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka7.34±0.20(Predicted)
form powder
color Purple
Safety Information
ToxicityLD50 in male, female mice, rats (g/kg): 3.0 ± 1.0; 3.1 ± 0.1; >1.0 orally (Majlathova)
MSDS Information
Alkannin Usage And Synthesis
UsesAlkannin is a enantiomeric dye from Alkanna tinctoria and Lithospermum erythrorhizon, which has known as dyestuff, wound healing, anti-inflammatory, anti-bacterial and anti-tumor substances.
UsesAlkannin (cas# 23444-65-7) inhibits proliferation, migration and invasion of human Huh7 and Hep3B2.1-7 hepatocellular carcinoma cells via regulation of miR92a. It is also useful in the application of macromolecular crowding to investigate naphthoquinones shikonin, naphthazarin and related analogs for treatment of dermal scars in human.
DefinitionChEBI: Alkannin is a hydroxy-1,4-naphthoquinone.
Alkannin Preparation Products And Raw materials
5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione Shikalkin DEOXYSHIKONIN Shikonin Methyl cyclopentenolone (BETA,BETA-DIMETHYLACRYL)SHIKONIN Naphthalene ISOBUTYRYLSHIKONIN 6-Methyl-5-hepten-2-one ISOVALERYLSHIKONIN 5,8-Dihydroxy-2-[1-hydroxy-4-(2H3)methyl(3,5,5,5-2H4)-3-penten-1-yl]-1,4-naphthoquinone 2,6-DIMETHYLNAPHTHALENE Alkannin 2-Methylnaphthalene Allyl methacrylate ACETYLSHIKONIN CHLOROPHOSPHONAZO III METHYLCYCLOPENTADIENE DIMER

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