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| | ACETONYLTRIPHENYLPHOSPHONIUM CHLORIDE Basic information |
| | ACETONYLTRIPHENYLPHOSPHONIUM CHLORIDE Chemical Properties |
| Melting point | 243-245 °C(lit.) | | storage temp. | Store below +30°C. | | form | solid | | color | White to Light yellow to Light orange | | Water Solubility | Soluble in hot water. | | Sensitive | Hygroscopic | | CAS DataBase Reference | 1235-21-8(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 22-24/25-S24/25-S22-60-37-26 | | WGK Germany | 3 | | RTECS | TA1841000 | | F | 3 | | HS Code | 29319019 | | Toxicity | mouse,LD50,intravenous,56mg/kg (56mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#01535, |
| | ACETONYLTRIPHENYLPHOSPHONIUM CHLORIDE Usage And Synthesis |
| Chemical Properties | WHITE TO SLIGHTLY BEIGE FINE CRYSTALLINE POWDER | | Uses | Acetonyltriphenylphosphonium chloride is used to investigate the antimycobacterial activities of Me alkenyl quinolones. It is used as a reactant for synthesis of unsaturated esters and ketones containing multiple aromatic and heteroaromatic rings using Suzuki coupling - Wittig olefination. | | Uses | Used to investigate the antimycobacterial activities of Me alkenyl quinolones
Reactant for synthesis of:
- Unsaturated esters and ketones containing multiple aromatic and heteroaromatic rings using Suzuki coupling - Wittig olefination
- Fused oxygen and nitrogen heterocycles via regioselective cyclocondensation
Reactant for Wittig olefinations | | Purification Methods | Recrystallise it from CHCl3/*C6H6/pet ether (b 60-80o) or by dissolving it in CHCl3 and pouring it into dry Et2O. max nm() 255(3,600), 262(3,700), 268(4,000) and 275(3,100). The iodide salt crystallises from H2O and has m 207-209o. [Ramirez & Dershowitz J Org Chem 22 41 1957.] Itisan IRRITANT and is hygroscopic. When shaken with a 10% aqueous solution of Na2CO3 (8hours) it gives acetylmethylene triphenyl phosphorane which is recrystallised from MeOH/H2O and after drying at 70o/0.1mm has m 205-206o. UV: nm() 268 (6600), 275 (6500) and 288 (5700), IR: max 1529 (s), 1470 (m), 1425 (s), max 1374 (m), 1105 and 978 (s) (cm-1). [Ramirez & Dershowitz J Org Chem 22 41, 44 1957, Beilstein 16 H 761, 16 II 373.] |
| | ACETONYLTRIPHENYLPHOSPHONIUM CHLORIDE Preparation Products And Raw materials |
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