3-PHENOXYANILINE

3-PHENOXYANILINE Basic information

Product Name:	3-PHENOXYANILINE
Synonyms:	3-AMINOPHENYL PHENYL ETHER;3-AMINODIPHENYL ETHER;3-PHENOXYANILINE;M-PHENOXYANILINE;3-phenoxy-benzenamin;Aniline, m-phenoxy-;m-Aminophenyl phenyl ether;Benzenamine, 3-phenoxy-
CAS:	3586-12-7
MF:	C12H11NO
MW:	185.22
EINECS:	222-715-9
Product Categories:	Amines;Building Blocks;C12;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Anilines, Aromatic Amines and Nitro Compounds
Mol File:	3586-12-7.mol

3-PHENOXYANILINE Chemical Properties

Melting point	41-44 °C (lit.)
Boiling point	329-330 °C (lit.)
density	1,158 g/cm³
refractive index	1.1583
Fp	>230 °F
pka	3.87±0.10(Predicted)
Water Solubility	Slightly soluble in water.
CAS DataBase Reference	3586-12-7(CAS DataBase Reference)
EPA Substance Registry System	Benzenamine, 3-phenoxy- (3586-12-7)

Safety Information

Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38
Safety Statements	26-37/39
WGK Germany	3
TSCA	Yes
HS Code	29222990

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

3-PHENOXYANILINE Usage And Synthesis

Uses	3-Phenoxyaniline is used as a reagent to synthesize nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway, these compounds are also potential anti-cancer agents. 3-Phenoxyaniline is also used as a reagent to synthesize inhibitors of the Dengue and West Nile virus proteases.

3-PHENOXYANILINE Preparation Products And Raw materials

Raw materials	Ethyl acetate-->Potassium carbonate-->Dimethyl sulfoxide-->Phenol-->Stannous chloride dihydrate-->1-Fluoro-3-nitrobenzene-->1-nitro-3-phenoxybenzene-->3-Bromonitrobenzene-->3-Bromoaniline-->Iodobenzene-->1-Iodo-3-nitrobenzene-->3-Aminophenol-->3-Chloroaniline
Preparation Products	3-PHENOXYPHENOL-->3-PHENOXYBROMOBENZENE-->Diphenyl ether

3,4'-Oxydianiline Nimesulide 3-(2,3,4,5,6-PENTAFLUOROPHENOXY)ANILINE HYDROCHLORIDE DISPERSE VIOLET 26 Direct Blue 106 LABOTEST-BB LT00159795 1,2-BIS(3-AMINOPHENOXY)BENZENE 2'-(Dibenzylamino)-6'-(diethylamino)fluoran 5(6)-Carboxytetramethylrhodamine succinimidyl ester 3-AMINO-4'-NITRODIPHENYL ETHER 2-(3,6-BIS-DIETHYLAMINO-9H-XANTHEN-9-YL)-BENZOIC ACID N1-[3-(2,3,4,5,6-PENTAFLUOROPHENOXY)PHENYL]-3-FLUOROBENZAMIDE 3-PHENOXYANILINE 2-chloro-6-nitri-3-phenoxyaniline 1,3-Bis(3-aminophenoxy)benzene 4,4'-BIS(3-AMINOPHENOXY)DIPHENYL SULFONE N1,N1-DIETHYL-5-CHLORO-2-(4-CHLOROPHENOXY)-4-NITROANILINE 5(6)-XRITC

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