Brassinolide

Brassinolide Basic information
Product Name:Brassinolide
Synonyms:5-ALPHA-CHOLESTANE-B-HOMO-7-OXA-24-BETA-METHYL-2-ALPHA, 3-ALPHA, 22-ALPHA, 23-ALPHA-TETROL-6-ONE;2-ALPHA,3-ALPHA,22R,23R,-TETRAHYDROXY-B-HOMO-7-OXA-5-ALPHA-ERGOSTAN-6-ONE;2-ALPHA,3-ALPHA,22R,23R-TETRADHYDROXY-24R-METHYL-B-HOMO-7-OXA-5-ALPHA-CHOLESTAN-6-ONE;(22R,23R,24R)-2-ALPHA,3-ALPHA,22,23-TETRAHYDROXY-24-METHYL-B-HOMO-7-OXA-5-ALPHA-CHOLESTAN-6-ONE;22R,23R,24R-2ALPHA,3ALPHA,22,28-TETRAHYDROXY-B-HOMO-7-OXA-5ALPHA-ERGOSTA-6-ONE;24R-BRASSINOLIDE;Epibrassinolide;(22R,23R,24S)-2α,3α,22,23-Tetrahydroxy-24-methyl-7-oxa-B-homo-5α-cholestan-6-one
CAS:72962-43-7
MF:C28H48O6
MW:480.68
EINECS:
Product Categories:fertilizer;Bio-Pesticide;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
Mol File:72962-43-7.mol
Brassinolide Structure
Brassinolide Chemical Properties
Melting point 200-204?C
alpha D27 +16°
Boiling point 633.7±55.0 °C(Predicted)
density 1.141±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka14.27±0.70(Predicted)
form Solid
color white to off-white
InChIKeyLUGSJEJPERVCLF-ZWSCYPDYSA-N
CAS DataBase Reference72962-43-7(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29322090
MSDS Information
ProviderLanguage
SigmaAldrich English
Brassinolide Usage And Synthesis
Chemical PropertiesOff-White Solid
UsesBrassinolide can be used as plant growth regulator.
UsesPlant growth regulator.
UsesBrassinolide has been used as a plant growth hormone.
DefinitionChEBI: Brassinolide is a 2alpha-hydroxy steroid, a 3alpha-hydroxy steroid, a 22-hydroxy steroid, a 23-hydroxy steroid and a brassinosteroid. It has a role as a plant growth stimulator and a plant hormone.
General DescriptionBrassinolide is a plant growth hormone and the most biologically active brassinosteroid (BR). It has been implicated in Auxin signaling. It has also been used for studying plant biosynthetic pathways. Brassinolide might also regulate water-transport properties of cell membranes in Arabidopsis thaliana.
Biological Activitybrassinolide is a plant growth regulator. plant growth regulators are naturally produced by plants and are critical for regulating their own growth. plant growth regulators act via modifying or controlling plant growth processes, such as leave and flower formation, stem elongation, as well as fruit development and ripening.
Biochem/physiol ActionsBrassinolide is a plant growth hormone that has been implicated in Auxin signaling. It has also been used for studying plant biosynthetic pathways.
in vitrobrassinolide induced the time and concentration-dependent cytotoxicity in pc-3 cells. the mode of such cell death appeared to be apoptosis predominately, as demonstrated by fluorescence, flow-cytometric analyses and transmission electron microscopes. moreover, caspase-3 activity was increased after brassinolide treatment obviously. western blot studies showed brassinolide treatment triggered a time-dependent decrease in the expression of bcl-2 [1].
in vivobrassinolide had the similar function of reducing the blood glucose levels as phenformin, but without the dose-dependent manner. the blood glucose levels showed significant differences after brassinolide treatment with different doses (200, 100, and 50 mg/kg). these results indicated that brassinolide could reduce the blood glucose levels without toxicity [2].
references[1] wu yd,lou yj. brassinolide, a plant sterol from pollen of brassica napus l., induces apoptosis in human prostate cancer pc-3 cells. pharmazie.2007 may;62(5):392-5.
[2] chen shi-ping, he jia, wang qi-jing, wang jian-dong, ye yan-li, xian li-jian. effect of brassinolide on levels of blood glucose in alloxan—induced diabetes rats. acta metallurgica sinica, 2009,v26(03): 21-23
Brassinolide Preparation Products And Raw materials
2-ethylhexyl 2-ethylhexanoate ε-Caprolactone FEMA 3505 3-(TRANS-4-N-PENTYLCYCLOHEXYL)PROPIONIC ACID FEMA 3506 METHYL 15-METHYLHEXADECANOATE 4-Hydroxycyclohexanecarboxylic acid DODECYL ISOBUTYRATE 2-ETHYLHEXANOIC ACID N-BUTYL ESTER Brassinolide octyl isononanoate CYCLOHEXANEPROPIONIC ACID METHYL ESTER decyl isovalerate isobutyl 2-ethylbutyrate isodecyl 2-ethylhexanoate 24-EPIBRASSINOLIDE,EPIBRASSINOLIDE 98% (HPLC),24R-BRASSINOLIDE,Epibrassinolide,(24R)-24-Epibrassinolide FEMA 3604 N-CAPRIC ACID ISOAMYL ESTER

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