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| | 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Basic information |
| Product Name: | 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT | | Synonyms: | 8-bromoadenosine-3’,5’-cyclicmonophosphate(8-br-camp),sodiumsalt;CAMP, 8-BR, NA;ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, 8-BROMO-, SODIUM SALT;8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT;8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT;8-BROMOADENOSINE-3',5'-CYCLOPHOSPHATE SODIUM SALT;8-BROMO-CAMP, NA;8-BROMO-CAMP, SODIUM SALT | | CAS: | 76939-46-3 | | MF: | C10H12BrN5NaO6P | | MW: | 432.1 | | EINECS: | | | Product Categories: | Cyclic Nucleotide related | | Mol File: | 76939-46-3.mol |  |
| | 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Chemical Properties |
| Melting point | >264°C )dec._ | | storage temp. | -20°C | | solubility | H2O: 100 mg/mL | | form | powder | | color | off-white | | Water Solubility | Soluble in water (100mM) | | BRN | 7739743 | | Stability: | Hygroscopic, Moisture Sensitive |
| | 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Usage And Synthesis |
| Chemical Properties | Off-white powder | | Uses | 8-Bromoadenosine 3′,5′-cyclic monophosphate sodium salt has been used:
- to study its effect on fas and caspase-3 mRNA expression and on P4 production in bovine mid luteal cell culture
- used to treat choriocarcinoma BeWo cell line and study its effect on cell viability, apoptosis and morphological changes in the nuclei
- in superfusion medium for head kidneys stimulation
| | General Description | 8-Bromoadenosine 3′:5′-cyclic monophosphate is a brominated cyclic mononucleotide. | | Biological Activity | Cell-permeable cAMP analog; activator of protein kinase A. Also available as part of the PKA Tocriset™ . | | Biochem/physiol Actions | Cell-permeable cAMP analog having greater resistance to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells. | | storage | -20°C (desiccate) |
| | 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Preparation Products And Raw materials |
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