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| | 4-Aminoguinoline Basic information |
| Product Name: | 4-Aminoguinoline | | Synonyms: | 4-AMinoquinoline hydrochloride;QUINOLIN-4-YLAMINE;4-QUINOLINAMINE;4-Quinolylamine;4-AMINOQUINOLINE;4-Aminoguinoline;Quinolin-4-amine;4-Aminoquinoline ,98% | | CAS: | 578-68-7 | | MF: | C9H8N2 | | MW: | 144.17 | | EINECS: | 640-116-4 | | Product Categories: | pharmacetical | | Mol File: | 578-68-7.mol |  |
| | 4-Aminoguinoline Chemical Properties |
| Melting point | 151.0 and le 155.0 °C | | Boiling point | 312.78°C (estimate) | | density | 1.1148 (estimate) | | refractive index | 1.7080 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | pka | 9.17(at 20℃) | | form | powder to crystalline | | color | White to Yellow to Orange | | CAS DataBase Reference | 578-68-7(CAS DataBase Reference) |
| | 4-Aminoguinoline Usage And Synthesis |
| Chemical Properties | Light brown to grey solid | | Uses | 4-Quinolinamine and its derivatives are commonly used as anti-malarial drugs and also have potential therapeutic effects on patients afflicted with arthritis (and/or related diseases). | | Synthesis Reference(s) | Journal of Medicinal Chemistry, 43, p. 4667, 2000 DOI: 10.1021/jm0002073
Tetrahedron Letters, 39, p. 1313, 1998 DOI: 10.1016/S0040-4039(97)10877-2 | | Purification Methods | It has been purified by zone refining and recrystallisation from *C6H6, EtOH or H2O. The hydrochloride has m 308o (from MeOH), and the picrate has m 277o (from EtOH). [Albert et al. J Chem Soc 2240 1948, Beilstein 22 III/IV 4611, 22/10 V 341.] |
| | 4-Aminoguinoline Preparation Products And Raw materials |
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