ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyrimidines Dihydroxypyrimidine 2-Hydroxypyrimidine hydrochloride

2-Hydroxypyrimidine hydrochloride

2-Hydroxypyrimidine hydrochloride Basic information
Product Name:2-Hydroxypyrimidine hydrochloride
Synonyms:2(1H)-PYRIMIDINONE HYDROCHLORIDE;2(1H)-PYRIMIDINONE, MONOHYDROCHLORIDE;2-PYRIMIDINOL HYDROCHLORIDE;2-PYRIMIDINOL MONOHYDROCHLORIDE;2-PYRIMIDINONE HYDROCHLORIDE;2-PYRIMIDONE HYDROCHLORIDE;2-OXOPYRIMIDINE HYDROCHLORIDE;2-HYDROXYPYRIMIDINIUM CHLORIDE
CAS:38353-09-2
MF:C4H5ClN2O
MW:132.55
EINECS:253-897-8
Product Categories:Pyrimidines;Heterocycle-Pyrimidine series;C4 to C5;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Pyridines, Pyrimidines, Purines and Pteredines;Pyrimidine;bc0001
Mol File:38353-09-2.mol
2-Hydroxypyrimidine hydrochloride Structure
2-Hydroxypyrimidine hydrochloride Chemical Properties
Melting point 200-205 °C (dec.)(lit.)
density 1.47 at 20℃
vapor pressure 0.004Pa at 25℃
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Crystalline Solid
color Light yellow to beige
Water Solubility almost transparency
Sensitive Hygroscopic
BRN 3560963
InChIKeyIAJINJSFYTZPEJ-UHFFFAOYSA-N
LogP-1.61 at 20.5℃ and pH5.6-6.5
CAS DataBase Reference38353-09-2(CAS DataBase Reference)
EPA Substance Registry System2(1H)-Pyrimidinone, monohydrochloride (38353-09-2)
Safety Information
Hazard Codes Xn
Risk Statements 36/37/38-40
Safety Statements 22-24/25-36-26
WGK Germany 3
TSCA Yes
HS Code 29335995
MSDS Information
ProviderLanguage
2-Pyrimidinol hydrochloride English
ACROS English
SigmaAldrich English
ALFA English
2-Hydroxypyrimidine hydrochloride Usage And Synthesis
Chemical Propertieslight yellow to beige crystalline solid
Uses2-Hydroxypyrimidine Hydrochloride, is used as a reagent in the synthesis of BI 207524, an indole diamide NS5B thumb pocket 1 inhibitor with improved potency for potential treatment of chronic hepatitis C virus infection.
2-Hydroxypyrimidine hydrochloride Preparation Products And Raw materials
Preparation Products5-BROMO-2-HYDROXYPYRIMIDINE-->5-Bromo-2-iodopyrimidine-->2,5-Dibromopyrimidine
2-Hydroxy-4-methylpyrimidine hydrochloride 4,6-DIMETHYL-2-PYRIMIDINYL 2,4-DICHLOROBENZENECARBOXYLATE 6-CHLORO-2,4-DIMETHOXYPYRIMIDINE Pyridine hydrochloride Triethylamine hydrochloride D-Glucosamine hydrochloride 4,6-DIMETHYL-2-PYRIMIDINYL 2,4,6-TRICHLOROBENZENECARBOXYLATE 2-Hydroxypyrimidine Topotecan hydrochloride Methoxyammonium chloride 4,6-DIMETHYL-2-HYDROXYPYRIMIDINE HYDROCHLORIDE,4,6-DIMETHYL-2-HYDROXYPYRIMIDINE HYDROCHLORIDE 97+% 2-Hydroxypyrimidine hydrochloride A-[(5-CHLOROPYRIMIDIN-2-YL)OXY]-2,3-DIHYDRO-5-BENZOFURANACETIC ACID, ETHYL ESTER Pyrimidine 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL 4-Hydroxyaniline hydrochloride N-(4-CHLOROPHENYL)-2-[(4,6-DIMETHYLPYRIMIDIN-2-YL)OXY]-N-ISOPROPYLACETAMIDE N-(2-CHLOROPHENYL)-2-[(4,6-DIMETHYLPYRIMIDIN-2-YL)OXY]-N-ISOPROPYLACETAMIDE
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